DisGeNET - a database of gene-disease associations

Source: UNIPROT

Disease: PARKINSON DISEASE, LATE-ONSET ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs387907571

DNAJC13

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.800

GeneticVariation

UNIPROT

dbSNP:

rs1056737920

TMEM230

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

dbSNP:

rs145242123

DNAJC13

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

DNAJC13 genetic variants in parkinsonism.

25393719

2015

dbSNP:

rs145242123

DNAJC13

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

DNAJC13 mutations in Parkinson disease.

24218364

2014

dbSNP:

rs146930051

DNAJC13

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

DNAJC13 genetic variants in parkinsonism.

25393719

2015

dbSNP:

rs146930051

DNAJC13

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

DNAJC13 mutations in Parkinson disease.

24218364

2014

dbSNP:

rs150562946

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.

29311685

2018

dbSNP:

rs150562946

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

19966284

2010

dbSNP:

rs150562946

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Parkin mutations and susceptibility alleles in late-onset Parkinson's disease.

12730996

2003

dbSNP:

rs150562946

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease.

12629236

2003

dbSNP:

rs34424986

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.

29311685

2018

dbSNP:

rs34424986

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

19966284

2010

dbSNP:

rs34424986

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Parkin mutations and susceptibility alleles in late-onset Parkinson's disease.

12730996

2003

dbSNP:

rs34424986

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease.

12629236

2003

dbSNP:

rs368134308

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.

29311685

2018

dbSNP:

rs368134308

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

19966284

2010

dbSNP:

rs368134308

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Parkin mutations and susceptibility alleles in late-onset Parkinson's disease.

12730996

2003

dbSNP:

rs368134308

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease.

12629236

2003

dbSNP:

rs72480422

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology.

29311685

2018

dbSNP:

rs72480422

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

19966284

2010

dbSNP:

rs72480422

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Parkin mutations and susceptibility alleles in late-onset Parkinson's disease.

12730996

2003

dbSNP:

rs72480422

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease.

12629236

2003

dbSNP:

rs747427602

PRKN

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

dbSNP:

rs764786986

TMEM230

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT

Identification of TMEM230 mutations in familial Parkinson's disease.

27270108

2016

dbSNP:

rs766013346

DNAJC13

CUI:	C3160718
Disease:	PARKINSON DISEASE, LATE-ONSET

PARKINSON DISEASE, LATE-ONSET

0.700

GeneticVariation

UNIPROT