Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2255336
rs2255336
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE Prevalence of the NKG2D Thr72Ala polymorphism in patients with systemic lupus erythematosus. 21598106

2012
dbSNP: rs2255336
rs2255336
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.020 GeneticVariation BEFREE In conclusion, based on our study results, SLE is associated with the SNP rs2255336 of NKG2D. 19735685

2010
dbSNP: rs11053781
rs11053781
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C0220668
Disease: Congenital contractural arachnodactyly
Congenital contractural arachnodactyly 		0.010 GeneticVariation BEFREE Two of the NKG2D SNPs were associated with an increased risk of CCA: rs11053781 [odds ratio (OR) = 2.08, 95% confidence interval (CI) = 1.31-3.29, corrected P (P(c)) = 0.011] and rs2617167 (OR = 2.32, 95% CI = 1.47-3.66, P(c) = 0.0020). 18023027

2008
dbSNP: rs2255336
rs2255336
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C0158945
Disease: Congenital cytomegalovirus infection
Congenital cytomegalovirus infection 		0.010 GeneticVariation BEFREE A Thr72Ala polymorphism in the NKG2D gene is associated with early symptomatic congenital cytomegalovirus disease. 25861030

2015
dbSNP: rs2255336
rs2255336
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C4048328
Disease: cervical cancer
cervical cancer 		0.010 GeneticVariation BEFREE Using polymerase chain reaction-restriction fragment length polymorphisms, we examined the NKG2D Thr72Ala polymorphism in patients with cervical cancer (n=353) and controls (n=366) in a Polish population. 22480139

2012
dbSNP: rs2255336
rs2255336
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma 		0.010 GeneticVariation BEFREE Using polymerase chain reaction-restriction fragment length polymorphisms, we examined the NKG2D Thr72Ala polymorphism in patients with cervical cancer (n=353) and controls (n=366) in a Polish population. 22480139

2012
dbSNP: rs2255336
rs2255336
KLRK1 ; KLRC4-KLRK1 ; LOC101928100
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix 		0.010 GeneticVariation BEFREE Using polymerase chain reaction-restriction fragment length polymorphisms, we examined the NKG2D Thr72Ala polymorphism in patients with cervical cancer (n=353) and controls (n=366) in a Polish population. 22480139

2012
dbSNP: rs2617160
rs2617160
KLRC4-KLRK1 ; LOC101928100
CUI: C0524909
Disease: Hepatitis B, Chronic
Hepatitis B, Chronic 		0.010 GeneticVariation BEFREE Single marker association analysis was conducted and the SNP rs2617160 with a TT genotype in NKG2D was associated significantly with an increased risk of chronic hepatitis B (P = 0.044; OR = 1.49; 95% CI = 1.01-2.19). 20648603

2010