|
rs28834970
|
|
Alzheimer's Disease
|
C |
0.830 |
GeneticVariation
|
GWASCAT |
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.
|
30617256 |
2019 |
|
rs28834970
|
|
Alzheimer's Disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.
|
31473137 |
2019 |
|
rs28834970
|
|
Alzheimer's Disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
The genotypes rs6733839 in the <i>BIN1</i> gene and rs28834970 in the <i>PTK2B</i> gene approached significance in the PENN cohort and were significantly associated with reduced AD risk in the NACC cohort.
|
30128317 |
2018 |
|
rs28834970
|
|
Alzheimer's Disease
|
|
0.830 |
GeneticVariation
|
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs28834970
|
|
Alzheimer's Disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
A number of genetic variants have previously been identified and associated with the risk of Alzheimer's disease (AD), including rs10838725 in CELF1, rs28834970 in PTK2B, rs17125944 in FERMT2, and rs10410544 in SIRT2 based on genome-wide association studies.
|
30144538 |
2018 |
|
rs28834970
|
|
Alzheimer's Disease
|
|
0.830 |
GeneticVariation
|
BEFREE |
Our results showed no significant differences in the frequency of rs28834970 alleles and genotypes between AD cases and controls.
|
27080426 |
2016 |
|
rs28834970
|
|
Alzheimer's Disease
|
C |
0.830 |
GeneticVariation
|
GWASCAT |
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
|
24162737 |
2013 |
|
rs28834970
|
|
Alzheimer's Disease
|
C |
0.830 |
GeneticVariation
|
GWASDB |
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
|
24162737 |
2013 |
|
rs10109834
|
|
Alzheimer's Disease
|
|
0.700 |
GeneticVariation
|
GWASCAT |
GWAS on family history of Alzheimer's disease.
|
29777097 |
2018 |
|
rs117176448
|
|
Body mass index
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs117176448
|
|
Body mass index
|
C |
0.700 |
GeneticVariation
|
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
|
rs11776693
|
|
Eosinophil count procedure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs17057051
|
|
Inflammatory Bowel Diseases
|
A |
0.700 |
GeneticVariation
|
GWASCAT |
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
|
26192919 |
2015 |
|
rs2322599
|
|
Takayasu Arteritis
|
G |
0.700 |
GeneticVariation
|
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs6987305
|
|
White Blood Cell Count procedure
|
|
0.700 |
GeneticVariation
|
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |
|
rs28834970
|
|
AURAL ATRESIA, CONGENITAL
|
|
0.010 |
GeneticVariation
|
BEFREE |
We observed significant associations of CAA pathology with APOEɛ4 and PTK2B rs28834970.
|
31256143 |
2019 |
|
rs28834970
|
|
Alzheimer Disease, Late Onset
|
|
0.010 |
GeneticVariation
|
BEFREE |
Finally, we found rs6656401-rs3865444 (CR1-CD33) pairs were significantly associated with decreasing LOAD risk, while rs28834970-rs6656401 (PTK2B-CR1), and rs28834970-rs6656401 (PTK2B-CD33) were associated with increasing LOAD risk.
|
26680604 |
2015 |
|
rs41316468
|
|
Cardiovascular Diseases
|
|
0.010 |
GeneticVariation
|
BEFREE |
Several of these SNPs, such as rs6141803 of COMMD7 and rs41316468 in PKT2B, have independently confirmed associations with cardiovascular diseases (CVDs) according to other unrelated studies, suggesting that our pipeline is robust in identifying key genetic variants.
|
28441463 |
2017 |
|
rs751019
|
|
Hypertensive disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Another polymorphism, 53484A>C (K838T), in linkage disequilibrium with -22A>G showed a marginal association with hypertension in men (AA vs. AC+CC: odds ratio=1.25; 95% confidence interval: 0.99-1.57; P=0.059).
|
18075463 |
2007 |