Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1047781
rs1047781
FUT2 ; LOC105447645
CUI: C0202252
Disease: VITAMIN B12 MEASUREMENT
VITAMIN B12 MEASUREMENT 		0.800 GeneticVariation GWASCAT In addition, we also confirmed the association with the serum level of VitB12 for the previously reported FUT2 gene and identified one novel non-synonymous single-nucleotide polymorphism in FUT2 gene in this Chinese population (19q13.33; rs1047781; P= 3.62 × 10(-36)). 22367966

2012
dbSNP: rs281377
rs281377
FUT2 ; LOC105447645
CUI: C0201850
Disease: Alkaline phosphatase measurement
Alkaline phosphatase measurement 		T 0.800 GeneticVariation GWASCAT Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. 22001757

2011
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		A 0.800 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422

2018
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C0202252
Disease: VITAMIN B12 MEASUREMENT
VITAMIN B12 MEASUREMENT 		C 0.800 GeneticVariation GWASCAT Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial. 25147783

2014
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		G 0.800 GeneticVariation GWASCAT Discovery and refinement of loci associated with lipid levels. 24097068

2013
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		G 0.800 GeneticVariation GWASCAT Biological, clinical and population relevance of 95 loci for blood lipids. 20686565

2010
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C0202252
Disease: VITAMIN B12 MEASUREMENT
VITAMIN B12 MEASUREMENT 		A 0.800 GeneticVariation GWASCAT We identified a strong association (P = 5.36 x 10(-17)) between rs492602 in FUT2 and plasma vitamin B(12) levels in a genome-wide scan (n = 1,658) and an independent replication sample (n = 1,059) from the Nurses' Health Study. 18776911

2008
dbSNP: rs504963
rs504963
FUT2 ; LOC105447645
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.800 GeneticVariation GWASCAT Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. 20570966

2010
dbSNP: rs516246
rs516246
FUT2 ; LOC105447645
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908

2017
dbSNP: rs516246
rs516246
FUT2 ; LOC105447645
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		A 0.800 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919

2015
dbSNP: rs516246
rs516246
FUT2 ; LOC105447645
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		T 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233

2012
dbSNP: rs516246
rs516246
FUT2 ; LOC105447645
CUI: C1278049
Disease: Serum gamma-glutamyl transferase measurement
Serum gamma-glutamyl transferase measurement 		T 0.800 GeneticVariation GWASCAT Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. 22001757

2011
dbSNP: rs602662
rs602662
FUT2 ; LOC105447645
CUI: C0202252
Disease: VITAMIN B12 MEASUREMENT
VITAMIN B12 MEASUREMENT 		A 0.800 GeneticVariation GWASCAT GWAS identifies population-specific new regulatory variants in FUT6 associated with plasma B12 concentrations in Indians. 28334792

2017
dbSNP: rs602662
rs602662
FUT2 ; LOC105447645
CUI: C0202252
Disease: VITAMIN B12 MEASUREMENT
VITAMIN B12 MEASUREMENT 		0.800 GeneticVariation GWASCAT On chromosome 19q13, we confirm the association of plasma vitamin B12 with rs602662 and rs492602 (P-value = 1.83 x 10(-15) and 1.30 x 10(-14), respectively) in strong linkage disequilibrium (LD) with rs601338 (P = 6.92 x 10(-15)), the FUT2 W143X nonsense mutation. 19744961

2009
dbSNP: rs602662
rs602662
FUT2 ; LOC105447645
CUI: C0202252
Disease: VITAMIN B12 MEASUREMENT
VITAMIN B12 MEASUREMENT 		A 0.800 GeneticVariation GWASCAT Polymorphisms in the ALPL gene (rs4654748, p = 8.30 x 10(-18)) were associated with vitamin B6 and FUT2 (rs602662, [corrected] p = 2.83 x 10(-20)) with vitamin B12 serum levels. 19303062

2009
dbSNP: rs602662
rs602662
FUT2 ; LOC105447645
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		G 0.710 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs602662
rs602662
FUT2 ; LOC105447645
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		G 0.710 GeneticVariation GWASCAT Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. 26301688

2015
dbSNP: rs1047781
rs1047781
FUT2 ; LOC105447645
CUI: C0033860
Disease: Psoriasis
Psoriasis 		C 0.700 GeneticVariation GWASCAT Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. 25574825

2015
dbSNP: rs35106244
rs35106244
FUT2
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs35106244
rs35106244
FUT2
CUI: C0011991
Disease: Diarrhea
Diarrhea 		T 0.700 GeneticVariation GWASCAT A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways. 27559109

2016
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		A 0.700 GeneticVariation GWASCAT Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. 30926973

2019
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		G 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		A 0.700 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422

2018
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		A 0.700 GeneticVariation GWASCAT A large electronic-health-record-based genome-wide study of serum lipids. 29507422

2018
dbSNP: rs492602
rs492602
FUT2 ; LOC105447645
CUI: C0033860
Disease: Psoriasis
Psoriasis 		G 0.700 GeneticVariation GWASCAT Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. 28537254

2017