|
rs8176719
|
|
Venous Thromboembolism
|
G |
0.830 |
GeneticVariation
|
GWASCAT |
ABO re-sequencing identified 15 novel single nucleotide variations (SNV) in ABO intron 6 and the ABO 3' UTR that were strongly associated with VTE (P<10(-4)) and belonged to three distinct linkage disequilibrium (LD) blocks; none were in LD with ABO rs8176719 or rs2519093.
|
22672568 |
2012 |
|
rs2519093
|
|
Venous Thromboembolism
|
T |
0.820 |
GeneticVariation
|
GWASCAT |
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
|
31420334 |
2019 |
|
rs2519093
|
|
Venous Thromboembolism
|
T |
0.820 |
GeneticVariation
|
GWASCAT |
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor.
|
28373160 |
2017 |
|
rs2519093
|
|
Venous Thromboembolism
|
A |
0.820 |
GeneticVariation
|
GWASCAT |
ABO re-sequencing identified 15 novel single nucleotide variations (SNV) in ABO intron 6 and the ABO 3' UTR that were strongly associated with VTE (P<10(-4)) and belonged to three distinct linkage disequilibrium (LD) blocks; none were in LD with ABO rs8176719 or rs2519093.
|
22672568 |
2012 |
|
rs505922
|
|
Duodenal Ulcer
|
T |
0.810 |
GeneticVariation
|
GWASCAT |
The T allele of rs2294008 encodes a translation initiation codon upstream of the reported site and changes protein localization from the cytoplasm to the cell surface. rs505922 at ABO was also associated with duodenal ulcer in a recessive model (OR = 1.32; P = 1.15 × 10(-10)).
|
22387998 |
2012 |
|
rs505922
|
|
von Willebrand's factor (lab test)
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke.
|
28495826 |
2017 |
|
rs505922
|
|
Graves Disease
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis.
|
23612905 |
2013 |
|
rs505922
|
|
von Willebrand's factor (lab test)
|
T |
0.800 |
GeneticVariation
|
GWASCAT |
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
|
23381943 |
2013 |
|
rs505922
|
|
Venous Thromboembolism
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Genetics of venous thrombosis: insights from a new genome wide association study.
|
21980494 |
2011 |
|
rs505922
|
|
Venous Thromboembolism
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Common susceptibility alleles are unlikely to contribute as strongly as the FV and ABO loci to VTE risk: results from a GWAS approach.
|
19278955 |
2009 |
|
rs507666
|
|
Serum total cholesterol measurement
|
|
0.800 |
GeneticVariation
|
GWASCAT |
Genetic analyses of diverse populations improves discovery for complex traits.
|
31217584 |
2019 |
|
rs507666
|
|
Serum total cholesterol measurement
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
A large electronic-health-record-based genome-wide study of serum lipids.
|
29507422 |
2018 |
|
rs507666
|
|
Serum total cholesterol measurement
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
The impact of low-frequency and rare variants on lipid levels.
|
25961943 |
2015 |
|
rs507666
|
|
Serum total cholesterol measurement
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
A genome wide association study identifies common variants associated with lipid levels in the Chinese population.
|
24386095 |
2013 |
|
rs514659
|
|
Coronary heart disease
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies.
|
21239051 |
2011 |
|
rs529565
|
|
Venous Thromboembolism
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
|
26908601 |
2016 |
|
rs529565
|
|
Venous Thromboembolism
|
C |
0.800 |
GeneticVariation
|
GWASCAT |
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.
|
25772935 |
2015 |
|
rs612169
|
|
von Willebrand's factor (lab test)
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
Connecting genetic risk to disease end points through the human blood plasma proteome.
|
28240269 |
2017 |
|
rs643434
|
|
C-reactive protein measurement
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
|
30388399 |
2018 |
|
rs643434
|
|
von Willebrand's factor (lab test)
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
|
23381943 |
2013 |
|
rs644234
|
|
Protein measurement
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study of circulating galectin-3.
|
23056639 |
2012 |
|
rs657152
|
|
Thyroid stimulating hormone measurement
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.
|
23408906 |
2013 |
|
rs687289
|
|
von Willebrand's factor (lab test)
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.
|
30586737 |
2019 |
|
rs687289
|
|
Venous Thromboembolism
|
A |
0.800 |
GeneticVariation
|
GWASCAT |
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
|
31420334 |
2019 |
|
rs687621
|
|
Venous Thromboembolism
|
G |
0.800 |
GeneticVariation
|
GWASCAT |
A genome-wide association study for venous thromboembolism: the extended cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium.
|
23650146 |
2013 |