Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1292037
rs1292037
Secondary malignant neoplasm of lymph node
0.010 GeneticVariation BEFREE The influencing factors of resistance to cisplatin plus paclitaxel included maximum lesion diameter, tumor stage, lymph node metastasis and rs1292037 (odds ratio [OR] = 14.047, 95% CI = 5.694-34.653; OR = 5.873, 95% CI = 3.104-11.110; OR = 3.574, 95% CI = 1.554-8.216; OR = 2.449, 95% CI = 1.052-5.705). 30447706

2018

dbSNP: rs1292037
rs1292037
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.010 GeneticVariation BEFREE In addition to that, the G allele at rs1292037 (A > G) locus increases the risk of preoperative chemoresistance to cisplatin plus paclitaxel and is a poor prognostic factor for patients with CC. 30447706

2018

dbSNP: rs1292037
rs1292037
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.010 GeneticVariation BEFREE In addition to that, the G allele at rs1292037 (A > G) locus increases the risk of preoperative chemoresistance to cisplatin plus paclitaxel and is a poor prognostic factor for patients with CC. 30447706

2018

dbSNP: rs1292037
rs1292037
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 GeneticVariation BEFREE The risk factors of prognosis included rs1292037 (A > G) locus, tumor stage, maximum lesion diameter and lymph node metastasis (hazard ratio [HR] = 1.819, 95% CI = 1.127-2.935; HR = 1.504, 95% CI = 1.070-2.114; HR = 1.671, 95% CI = 1.038-2.689; HR = 3.043, 95% CI = 1.783-5.193). 30447706

2018

dbSNP: rs1292037
rs1292037
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 GeneticVariation BEFREE In addition to that, the G allele at rs1292037 (A > G) locus increases the risk of preoperative chemoresistance to cisplatin plus paclitaxel and is a poor prognostic factor for patients with CC. 30447706

2018

dbSNP: rs1292037
rs1292037
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke
0.010 GeneticVariation BEFREE We investigated whether three common microRNA polymorphisms (miR-21T>C [rs1292037], miR-126G>A [rs4636297] and miR-605T>C [rs2043556]) were associated with ischemic stroke (IS) risk in a Chinese population. 29221163

2017

dbSNP: rs13137
rs13137
CUI: C0243026
Disease: Sepsis
Sepsis
0.010 GeneticVariation BEFREE The T allele of the miR-21 SNP rs13137 and the T allele of the miR-145 SNP rs353291 (OR = 0.685, 95% CI = 0.566-0.820, P < .001) were found to be a protective factor for sepsis (OR = 0.755, 95% CI = 0.632-0.896, P < .001). 31415369

2019

dbSNP: rs13137
rs13137
CUI: C0036690
Disease: Septicemia
Septicemia
0.010 GeneticVariation BEFREE The T allele of the miR-21 SNP rs13137 and the T allele of the miR-145 SNP rs353291 (OR = 0.685, 95% CI = 0.566-0.820, P < .001) were found to be a protective factor for sepsis (OR = 0.755, 95% CI = 0.632-0.896, P < .001). 31415369

2019

dbSNP: rs13137
rs13137
CUI: C0007847
Disease: Malignant tumor of cervix
Malignant tumor of cervix
0.010 GeneticVariation BEFREE We investigated correlations of miR-21 gene polymorphisms including rs1292037 (A > G) and rs13137 (A > T) with the chemosensitivity to cisplatin plus paclitaxel, and prognosis before cervical cancer (CC) surgery, which may provide a novel target for prevention and treatment of CC. 30447706

2018

dbSNP: rs13137
rs13137
CUI: C4048328
Disease: cervical cancer
cervical cancer
0.010 GeneticVariation BEFREE We investigated correlations of miR-21 gene polymorphisms including rs1292037 (A > G) and rs13137 (A > T) with the chemosensitivity to cisplatin plus paclitaxel, and prognosis before cervical cancer (CC) surgery, which may provide a novel target for prevention and treatment of CC. 30447706

2018

dbSNP: rs13137
rs13137
CUI: C0302592
Disease: Cervix carcinoma
Cervix carcinoma
0.010 GeneticVariation BEFREE We investigated correlations of miR-21 gene polymorphisms including rs1292037 (A > G) and rs13137 (A > T) with the chemosensitivity to cisplatin plus paclitaxel, and prognosis before cervical cancer (CC) surgery, which may provide a novel target for prevention and treatment of CC. 30447706

2018