Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4795067
rs4795067
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.820 GeneticVariation GWASCAT Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. 25574825

2015
dbSNP: rs4795067
rs4795067
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.820 GeneticVariation BEFREE Recently, genome-wide association studies identified a novel psoriasis susceptibility locus tagged by two single-nucleotide polymorphisms (SNPs) rs4795067 and rs28998802, both of which are in the intronic region of inducible nitric oxide synthase (iNOS) gene. 25663087

2015
dbSNP: rs4795067
rs4795067
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		G 0.820 GeneticVariation GWASCAT Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. 25903422

2015
dbSNP: rs4795067
rs4795067
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.820 GeneticVariation BEFREE Additionally, we found genome-wide significant association to the previously reported psoriasis risk loci; NOS2 (rs4795067, p=5.27×10(-9)). 25923216

2015
dbSNP: rs4795067
rs4795067
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		G 0.820 GeneticVariation GWASDB All three loci were also associated with psoriatic arthritis (rs4795067, combined P = 1 × 10⁻⁵; rs10782001, combined P = 4 × 10⁻⁸; and rs12586317, combined P = 6 × 1⁻⁵) and purely cutaneous psoriasis (rs4795067, combined P = 1 × 10⁻⁸; rs10782001, combined P = 2 × 10⁻⁶; and rs12586317, combined P = 1 × 10⁻⁶). 20953189

2010
dbSNP: rs4795067
rs4795067
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		G 0.820 GeneticVariation GWASCAT All three loci were also associated with psoriatic arthritis (rs4795067, combined P = 1 × 10⁻⁵; rs10782001, combined P = 4 × 10⁻⁸; and rs12586317, combined P = 6 × 1⁻⁵) and purely cutaneous psoriasis (rs4795067, combined P = 1 × 10⁻⁸; rs10782001, combined P = 2 × 10⁻⁶; and rs12586317, combined P = 1 × 10⁻⁶). 20953189

2010
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.810 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.810 GeneticVariation BEFREE Recently, genome-wide association studies identified a novel psoriasis susceptibility locus tagged by two single-nucleotide polymorphisms (SNPs) rs4795067 and rs28998802, both of which are in the intronic region of inducible nitric oxide synthase (iNOS) gene. 25663087

2015
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.810 GeneticVariation GWASDB Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594

2012
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		A 0.810 GeneticVariation GWASCAT Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. 23143594

2012
dbSNP: rs2297518
rs2297518
NOS2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		A 0.700 GeneticVariation GWASCAT Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. 23749187

2013
dbSNP: rs28998800
rs28998800
NOS2
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0008313
Disease: Cholangitis, Sclerosing
Cholangitis, Sclerosing 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs28998802
rs28998802
NOS2
CUI: C0263361
Disease: Psoriasis vulgaris
Psoriasis vulgaris 		A 0.700 GeneticVariation GWASCAT Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. 26626624

2015
dbSNP: rs7217335
rs7217335
NOS2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		A 0.700 GeneticVariation GWASCAT Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis. 30946743

2019
dbSNP: rs769900089
rs769900089
NOS2
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.700 GeneticVariation UNIPROT

dbSNP: rs8070472
rs8070472
NOS2
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs8070472
rs8070472
NOS2
CUI: C0428472
Disease: Serum HDL cholesterol measurement
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs9797244
rs9797244
NOS2
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs9797244
rs9797244
NOS2
CUI: C0008313
Disease: Cholangitis, Sclerosing
Cholangitis, Sclerosing 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs9797244
rs9797244
NOS2
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs9797244
rs9797244
NOS2
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016