Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11292716
rs11292716
PON1
CUI: C0201899
Disease: Aspartate aminotransferase measurement
Aspartate aminotransferase measurement 		0.700 GeneticVariation GWASCAT Connecting genetic risk to disease end points through the human blood plasma proteome. 28240269

2017
dbSNP: rs1157745
rs1157745
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs2057681
rs2057681
PON1
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		G 0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178

2013
dbSNP: rs2057681
rs2057681
PON1
CUI: C2257843
Disease: paraoxonase activity
paraoxonase activity 		G 0.700 GeneticVariation GWASDB Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk. 22982463

2012
dbSNP: rs2237583
rs2237583
PON1
CUI: C2257843
Disease: paraoxonase activity
paraoxonase activity 		0.700 GeneticVariation GWASDB Novel common and rare genetic determinants of paraoxonase activity: FTO, SERPINA12, and ITGAL. 23160181

2013
dbSNP: rs3917502
rs3917502
PON1
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs3917510
rs3917510
PON1
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs3917532
rs3917532
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs3917539
rs3917539
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		TAA 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs3917545
rs3917545
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs3917549
rs3917549
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs662
rs662
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		C 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs662
rs662
PON1
CUI: C1827841
Disease: Enzyme activity finding
Enzyme activity finding 		C 0.700 GeneticVariation CLINVAR

dbSNP: rs662
rs662
PON1
CUI: C1840169
Disease: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO 		C 0.700 SusceptibilityMutation CLINVAR

dbSNP: rs662
rs662
PON1
CUI: C3149706
Disease: CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO
CORONARY ARTERY SPASM 2, SUSCEPTIBILITY TO 		C 0.700 SusceptibilityMutation CLINVAR

dbSNP: rs705379
rs705379
PON1
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488

2018
dbSNP: rs757158
rs757158
PON1
CUI: C0201899
Disease: Aspartate aminotransferase measurement
Aspartate aminotransferase measurement 		T 0.700 GeneticVariation GWASCAT Connecting genetic risk to disease end points through the human blood plasma proteome. 28240269

2017
dbSNP: rs854560
rs854560
PON1
CUI: C2674665
Disease: MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5 (finding)
MICROVASCULAR COMPLICATIONS OF DIABETES, SUSCEPTIBILITY TO, 5 (finding) 		T 0.700 SusceptibilityMutation CLINVAR

dbSNP: rs854560
rs854560
PON1
CUI: C1840169
Disease: CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO
CORONARY ARTERY DISEASE, SUSCEPTIBILITY TO 		T 0.700 SusceptibilityMutation CLINVAR

dbSNP: rs854560
rs854560
PON1
CUI: C1827841
Disease: Enzyme activity finding
Enzyme activity finding 		T 0.700 GeneticVariation CLINVAR

dbSNP: rs854572
rs854572
PON1
CUI: C2257843
Disease: paraoxonase activity
paraoxonase activity 		C 0.700 GeneticVariation GWASDB Clinical and genetic association of serum paraoxonase and arylesterase activities with cardiovascular risk. 22982463

2012
dbSNP: rs662
rs662
PON1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 GeneticVariation BEFREE Therefore, Q192R polymorphism was more correlated with type 2 diabetes mellitus. 31102685

2019
dbSNP: rs662
rs662
PON1
CUI: C0948008
Disease: Ischemic stroke
Ischemic stroke 		0.100 GeneticVariation BEFREE In summary, this meta-analysis proved that PON1 rs854560 polymorphism could be used to identify individual with elevated susceptibility to IS, whereas rs662 polymorphism could be used to identify individual with elevated susceptibility to CAD. 31302193

2019
dbSNP: rs662
rs662
PON1
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.100 GeneticVariation BEFREE In summary, this meta-analysis proved that PON1 rs854560 polymorphism could be used to identify individual with elevated susceptibility to IS, whereas rs662 polymorphism could be used to identify individual with elevated susceptibility to CAD. 31302193

2019
dbSNP: rs662
rs662
PON1
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.100 GeneticVariation BEFREE PON1 (Q192R and L55M) polymorphisms may play a crucial role in pathogenesis and susceptibility of insulin resistance thus leads to the development of type 2 diabetes in South Indian population. 29409844

2018