Source: GWASCAT

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.870 GeneticVariation GWASCAT Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease. 28869590

2017
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.870 GeneticVariation GWASCAT Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. 24509480

2014
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		G 0.870 GeneticVariation GWASCAT A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. 22961080

2013
dbSNP: rs11263763
rs11263763
HNF1B
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		A 0.800 GeneticVariation GWASCAT Five endometrial cancer risk loci identified through genome-wide association analysis. 27135401

2016
dbSNP: rs11651052
rs11651052
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.800 GeneticVariation GWASCAT Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population. 30718926

2019
dbSNP: rs11651052
rs11651052
HNF1B
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma 		0.800 GeneticVariation GWASCAT GWAS meta-analysis of 16 852 women identifies new susceptibility locus for endometrial cancer. 27008869

2016
dbSNP: rs11651052
rs11651052
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		A 0.800 GeneticVariation GWASCAT Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. 22885922

2012
dbSNP: rs11651755
rs11651755
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		C 0.800 GeneticVariation GWASCAT Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes. 30054458

2018
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		A 0.800 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		A 0.800 GeneticVariation GWASCAT Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. 29892016

2018
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		A 0.800 GeneticVariation GWASCAT Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer. 26443449

2015
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0201544
Disease: Prostate specific antigen measurement
Prostate specific antigen measurement 		A 0.800 GeneticVariation GWASCAT Overall, we detected a genome-wide significant association between PSA levels and single-nucleotide polymorphisms (SNPs) at six loci: 5p15.33 (rs2736098), 10q11 (rs10993994), 10q26 (rs10788160), 12q24 (rs11067228), 17q12 (rs4430796), and 19q13.33 [rs17632542 (KLK3: I179T)], each with P(combined) <3 × 10(-10). 21160077

2010
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		A 0.800 GeneticVariation GWASCAT Multiple loci identified in a genome-wide association study of prostate cancer. 18264096

2008
dbSNP: rs4430796
rs4430796
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		A 0.800 GeneticVariation GWASCAT Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. 17603485

2007
dbSNP: rs7501939
rs7501939
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		C 0.740 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs7501939
rs7501939
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.740 GeneticVariation GWASCAT Genome-wide association study identifies five new susceptibility loci for prostate cancer in the Japanese population. 20676098

2010
dbSNP: rs7501939
rs7501939
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.740 GeneticVariation GWASCAT Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. 19767753

2009
dbSNP: rs7501939
rs7501939
HNF1B
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		C 0.740 GeneticVariation GWASCAT Multiple newly identified loci associated with prostate cancer susceptibility. 18264097

2008
dbSNP: rs11649743
rs11649743
HNF1B ; LOC105371754
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		G 0.730 GeneticVariation GWASCAT 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population. 31562322

2019
dbSNP: rs11649743
rs11649743
HNF1B ; LOC105371754
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		G 0.730 GeneticVariation GWASCAT A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences. 26034056

2015
dbSNP: rs7501939
rs7501939
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		0.720 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs11651755
rs11651755
HNF1B
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		C 0.710 GeneticVariation GWASCAT Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer. 28346442

2017
dbSNP: rs4795218
rs4795218
HNF1B ; LOC105371754
CUI: C0235974
Disease: Pancreatic carcinoma
Pancreatic carcinoma 		G 0.710 GeneticVariation GWASCAT Replication of 10 promising signals in up to 2737 patients and 4752 controls from the PANcreatic Disease ReseArch (PANDoRA) consortium yields new genome-wide significant loci: rs13303010 at 1p36.33 (NOC2L, P = 8.36 × 10<sup>-14</sup>), rs2941471 at 8q21.11 (HNF4G, P = 6.60 × 10<sup>-10</sup>), rs4795218 at 17q12 (HNF1B, P = 1.32 × 10<sup>-8</sup>), and rs1517037 at 18q21.32 (GRP, P = 3.28 × 10<sup>-8</sup>). rs78417682 is not statistically significantly associated with pancreatic cancer in PANDoRA. 29422604

2018
dbSNP: rs757210
rs757210
HNF1B
CUI: C0677886
Disease: Epithelial ovarian cancer
Epithelial ovarian cancer 		A 0.710 GeneticVariation GWASCAT Identification of six new susceptibility loci for invasive epithelial ovarian cancer. 25581431

2015
dbSNP: rs10908278
rs10908278
HNF1B
CUI: C0011860
Disease: Diabetes Mellitus, Non-Insulin-Dependent
Diabetes Mellitus, Non-Insulin-Dependent 		T 0.700 GeneticVariation GWASCAT Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes. 26818947

2016