Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs102275
rs102275
TMEM258
CUI: C0010346
Disease: Crohn Disease
Crohn Disease 		C 0.810 GeneticVariation GWASDB Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. 21102463

2010
dbSNP: rs102275
rs102275
TMEM258
CUI: C0202177
Disease: Phospholipid measurement
Phospholipid measurement 		T 0.800 GeneticVariation GWASDB Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. 23362303

2013
dbSNP: rs102275
rs102275
TMEM258
CUI: C0202177
Disease: Phospholipid measurement
Phospholipid measurement 		C 0.800 GeneticVariation GWASDB Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. 23362303

2013
dbSNP: rs102275
rs102275
TMEM258
CUI: C0392885
Disease: High density lipoprotein measurement
High density lipoprotein measurement 		0.800 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0202177
Disease: Phospholipid measurement
Phospholipid measurement 		0.800 GeneticVariation GWASDB Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. 22359512

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0202177
Disease: Phospholipid measurement
Phospholipid measurement 		T 0.800 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377

2011
dbSNP: rs102275
rs102275
TMEM258
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X 		0.800 GeneticVariation GWASDB A genome-wide association study of the metabolic syndrome in Indian Asian men. 20694148

2010
dbSNP: rs174537
rs174537
MYRF ; TMEM258
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		G 0.800 GeneticVariation GWASDB Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk. 24836286

2014
dbSNP: rs174537
rs174537
MYRF ; TMEM258
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.800 GeneticVariation GWASDB A null mutation in human APOC3 confers a favorable plasma lipid profile and apparent cardioprotection. 19074352

2008
dbSNP: rs102274
rs102274
TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178

2013
dbSNP: rs102275
rs102275
TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C1445957
Disease: Serum total cholesterol measurement
Serum total cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0428472
Disease: Serum HDL cholesterol measurement
Serum HDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0202117
Disease: Low density lipoprotein cholesterol measurement
Low density lipoprotein cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0202236
Disease: Triglycerides measurement
Triglycerides measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs102275
rs102275
TMEM258
CUI: C0428474
Disease: Serum LDL cholesterol measurement
Serum LDL cholesterol measurement 		0.700 GeneticVariation GWASDB Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. 23063622

2012
dbSNP: rs108499
rs108499
MYRF ; TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178

2013
dbSNP: rs108499
rs108499
MYRF ; TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs108499
rs108499
MYRF ; TMEM258
CUI: C0202177
Disease: Phospholipid measurement
Phospholipid measurement 		0.700 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377

2011
dbSNP: rs149803
rs149803
MYRF ; TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs149803
rs149803
MYRF ; TMEM258
CUI: C0202177
Disease: Phospholipid measurement
Phospholipid measurement 		0.700 GeneticVariation GWASDB Genetic loci associated with plasma phospholipid n-3 fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium. 21829377

2011
dbSNP: rs149804
rs149804
MYRF ; TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012
dbSNP: rs174528
rs174528
MYRF ; TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB A genome-wide assessment of variability in human serum metabolism. 23281178

2013
dbSNP: rs174528
rs174528
MYRF ; TMEM258
CUI: C0523465
Disease: Serum albumin measurement
Serum albumin measurement 		0.700 GeneticVariation GWASDB Genome-wide association study identifies multiple loci influencing human serum metabolite levels. 22286219

2012