|
rs1047840
|
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
For the rs1047840 polymorphism, in an ethnicity subgroup analysis, a significantly increased susceptibility to cancer for Asians was identified in all the genetic models, and for Caucasians in an allelic model.
|
27387683 |
2016 |
|
rs1047840
|
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
For the rs1047840 polymorphism, in an ethnicity subgroup analysis, a significantly increased susceptibility to cancer for Asians was identified in all the genetic models, and for Caucasians in an allelic model.
|
27387683 |
2016 |
|
rs1047840
|
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, Exo1 K589E Lys allele may be used as a novel biomarker for ca</span>ncer susceptibility, particularly in smokers.
|
24810280 |
2014 |
|
rs1047840
|
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups.
|
24761866 |
2014 |
|
rs1047840
|
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups.
|
24761866 |
2014 |
|
rs1047840
|
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
In conclusion, Exo1 K589E Lys allele may be used as a novel biomarker for ca</span>ncer susceptibility, particularly in smokers.
|
24810280 |
2014 |
|
rs1047840
|
|
Primary malignant neoplasm
|
|
0.040 |
GeneticVariation
|
BEFREE |
A guanine (G)/adenine (A) common single nucleotide polymorphism at first position of codon 589 in Exo 1 gene determines a glutamic acid (Glu, E) to lysine (Lys, K) (K589E) aminoacidic substitution which may alter cancer risk by influencing the activity of Exo 1 protein.
|
22205538 |
2012 |
|
rs1047840
|
|
Malignant Neoplasms
|
|
0.040 |
GeneticVariation
|
BEFREE |
A guanine (G)/adenine (A) common single nucleotide polymorphism at first position of codon 589 in Exo 1 gene determines a glutamic acid (Glu, E) to lysine (Lys, K) (K589E) aminoacidic substitution which may alter cancer risk by influencing the activity of Exo 1 protein.
|
22205538 |
2012 |
|
rs1047840
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups.
|
24761866 |
2014 |
|
rs1047840
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups.
|
24761866 |
2014 |
|
rs1047840
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
This meta-analysis suggests, for the first time, that the EXO1 Glu589Lys polymorphism is not associated with overall cancer susceptibility, although marginal associations were found for lung cancer and Asian subgroups.
|
24761866 |
2014 |
|
rs1047840
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results provide the first evidence that the A allele of Exo1 K589E may be associated with the development of lung cancer and may be a novel useful marker for primary prevention and anticancer intervention.
|
19331228 |
2009 |
|
rs1047840
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results provide the first evidence that the A allele of Exo1 K589E may be associated with the development of lung cancer and may be a novel useful marker for primary prevention and anticancer intervention.
|
19331228 |
2009 |
|
rs1047840
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
Our results provide the first evidence that the A allele of Exo1 K589E may be associated with the development of lung cancer and may be a novel useful marker for primary prevention and anticancer intervention.
|
19331228 |
2009 |
|
rs1047840
|
|
Malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
These results suggest that the EXO1 Glu589Lys polymorphism and its surrounding regions might be genetic susceptibility markers for lung cancer in this study population.
|
18079015 |
2008 |
|
rs1047840
|
|
Primary malignant neoplasm of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
These results suggest that the EXO1 Glu589Lys polymorphism and its surrounding regions might be genetic susceptibility markers for lung cancer in this study population.
|
18079015 |
2008 |
|
rs1047840
|
|
Carcinoma of lung
|
|
0.030 |
GeneticVariation
|
BEFREE |
These results suggest that the EXO1 Glu589Lys polymorphism and its surrounding regions might be genetic susceptibility markers for lung cancer in this study population.
|
18079015 |
2008 |
|
rs1047840
|
|
Prostate carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that CDH1 -160C/A and Exo1 K589E polymorphisms are associated with increased susceptibility to prostate cancer in Bangladeshi population.
|
30880589 |
2019 |
|
rs1047840
|
|
Malignant neoplasm of prostate
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our results suggest that CDH1 -160C/A and Exo1 K589E polymorphisms are associated with increased susceptibility to prostate cancer in Bangladeshi population.
|
30880589 |
2019 |
|
rs1047840
|
|
Squamous cell carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
We examined the influence of MLH1 c.-93G>A, MSH2 c.211 + 9C>G, MSH3 c.3133G>A and EXO1 c.1765G>A polymorphisms, involved in DNA mismatch repair (MMR), on head and neck (HN) squamous cell carcinoma (SCC) risk and prognosis.
|
25598504 |
2015 |
|
rs1047840
|
|
Malignant tumor of cervix
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings indicate that the SNPs of EXO1 K589E may contribute to cervical cancer carcinogenesis in Chinese populations.
|
22146767 |
2012 |
|
rs1047840
|
|
Cervix carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings indicate that the SNPs of EXO1 K589E may contribute to cervical cancer carcinogenesis in Chinese populations.
|
22146767 |
2012 |
|
rs1047840
|
|
Liver carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our data shows that the Lys/Lys genotype of the Exo 1 K589E polymorphism is associated with increased risk of HCC development in this Turkish population [odds ratio (OR) = 2.15, 95% confidence interval (CI): 1.13-4.09, P = 0.02].
|
22205538 |
2012 |
|
rs1047840
|
|
Carcinogenesis
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings indicate that the SNPs of EXO1 K589E may contribute to cervical cancer carcinogenesis in Chinese populations.
|
22146767 |
2012 |
|
rs1047840
|
|
cervical cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
These findings indicate that the SNPs of EXO1 K589E may contribute to cervical cancer carcinogenesis in Chinese populations.
|
22146767 |
2012 |