|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
The TCTCTG-rs9533156-rs2073618-rs2073617-rs4950928-rs2228570-rs1544410 haplotype was significantly associated with increased BC </span>risk (adjusted odds ratio = 8.33; 95% confidence interval, 1.32-52.46; P = .025) compared with controls.
|
30309792 |
2019 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The TCTCTG-rs9533156-rs2073618-rs2073617-rs4950928-rs2228570-rs1544410 haplotype was significantly associated with increased BC </span>risk (adjusted odds ratio = 8.33; 95% confidence interval, 1.32-52.46; P = .025) compared with controls.
|
30309792 |
2019 |
|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
Association of FokI (rs2228570) and BsmI (rs1544410) single nucleotide polymorphisms (SNPs) in VDR gene with the risk of breast cancer have been investigated in several studies, however, the published data are still inconsistent.
|
28780723 |
2018 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
Association of FokI (rs2228570) and BsmI (rs1544410) single nucleotide polymorphisms (SNPs) in VDR gene with the risk of breast cancer have been investigated in several studies, however, the published data are still inconsistent.
|
28780723 |
2018 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
Two common single nucleotide polymorphisms (SNPs) in the VDR gene, rs1544410 (BsmI) and rs2228570 (FokI), are inconsistently associated with breast cancer risk in Caucasian populations, while data for Asians are scarce.
|
26517870 |
2015 |
|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
Two common single nucleotide polymorphisms (SNPs) in the VDR gene, rs1544410 (BsmI) and rs2228570 (FokI), are inconsistently associated with breast cancer risk in Caucasian populations, while data for Asians are scarce.
|
26517870 |
2015 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The role of the rs1544410 polymorphism of vitamin D receptor gene in breast cancer susceptibility.
|
25064221 |
2014 |
|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
The role of the rs1544410 polymorphism of vitamin D receptor gene in breast cancer susceptibility.
|
25064221 |
2014 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
Sunlight measures were not associated with breast cancer risk, however significant interactions between time outdoors in the teen years and three unlinked genotypes were found for VDR (rs1544410, rs2228570) and CYP24A1 (rs1570669).
|
23393347 |
2013 |
|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
Sunlight measures were not associated with breast cancer risk, however significant interactions between time outdoors in the teen years and three unlinked genotypes were found for VDR (rs1544410, rs2228570) and CYP24A1 (rs1570669).
|
23393347 |
2013 |
|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
The most extensively studied SNPs including rs10735810, also known as rs2228570 (Fok1, VDR), rs1544410 (Bsm1, VDR), and rs2296241 (CYP24A1), were not associated with breast cancer risk.
|
21828234 |
2011 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
The most extensively studied SNPs including rs10735810, also known as rs2228570 (Fok1, VDR), rs1544410 (Bsm1, VDR), and rs2296241 (CYP24A1), were not associated with breast cancer risk.
|
21828234 |
2011 |
|
rs1544410
|
|
Malignant neoplasm of breast
|
|
0.070 |
GeneticVariation
|
BEFREE |
No association was noted between rs1544410 (BsmI) BB and breast cancer risk overall (OR, 0.98; 95% CI, 0.89-1.09), but the BB genotype was associated with a significantly lower risk of advanced breast cancer (OR, 0.74; 95% CI, 0.60-0.92).
|
19124512 |
2009 |
|
rs1544410
|
|
Breast Carcinoma
|
|
0.070 |
GeneticVariation
|
BEFREE |
No association was noted between rs1544410 (BsmI) BB and breast cancer risk overall (OR, 0.98; 95% CI, 0.89-1.09), but the BB genotype was associated with a significantly lower risk of advanced breast cancer (OR, 0.74; 95% CI, 0.60-0.92).
|
19124512 |
2009 |
|
rs1544410
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Our findings demonstrated that VDR ApaI (rs7975232) and VDR BsmI (rs1544410) polymorphisms are correlated with susceptibility to PCOS in the Asian population and VDR TaqI (rs731236), VDR FokI (rs2228570), VDR Tru9I (rs757343) did not reveal a relationship with the PCOS susceptibility.
|
30764792 |
2019 |
|
rs1544410
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil.
|
29669566 |
2018 |
|
rs1544410
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Present study investigated association between VDR gene BsmI A/G (rs1544410), ApaI A/C (rs7975232) and TaqI T/C (rs731236) single nucleotide polymorphisms and PCOS risk in South Indian women.
|
28868946 |
2018 |
|
rs1544410
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Odds ratios (ORs) with 95% confidence interval (CIs) were calculated to assess the association between VDR Fok I C/T (rs10735810), BsmI A/G (rs1544410), ApaI A/C (rs7975232), and TaqI T/C (rs731236) polymorphisms and PCOS risk.
|
30687119 |
2018 |
|
rs1544410
|
|
Polycystic Ovary Syndrome
|
|
0.050 |
GeneticVariation
|
BEFREE |
Classic PCOS phenotype is not associated with deficiency of endogenous vitamin D and VDR gene polymorphisms rs731236 (TaqI), rs7975232 (ApaI), rs1544410 (BsmI), rs10735810 (FokI): a case-control study of lower Silesian women.
|
26422783 |
2015 |
|
rs1544410
|
|
Osteoporosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Patients with osteoporosis were also three times more likely to carry the rs1544410 G/G genotype, when compared to controls.
|
29922235 |
2018 |
|
rs1544410
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
Thus, VDR (rs1544410) SNP was found to be associated with decreased serum (25[OH]D) levels in both micro-macrovascular complications of T2DM among South Indian Population.
|
29738868 |
2018 |
|
rs1544410
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
The G-allele and GG genotype of rs2228570 and T-allele and TT genotype of rs1544410 SNPs were associated with T2DM.
|
28323045 |
2018 |
|
rs1544410
|
|
Osteoporosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Lack of association between vitamin D receptor polymorphisms ApaI (rs7975232) and BsmI (rs1544410) and osteoporosis among the Han Chinese population: A meta-analysis.
|
27914610 |
2016 |
|
rs1544410
|
|
Osteoporosis
|
|
0.040 |
GeneticVariation
|
BEFREE |
Our results indicate that rs1544410 polymorphisms do not account significantly for the changes in bone mass in Spanish women with osteoporosis undergoing treatment.
|
26393357 |
2015 |
|
rs1544410
|
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.040 |
GeneticVariation
|
BEFREE |
Patient-control haplotype analyses using the SHEsis online haplotype analysis software showed that the G allele frequency of rs1544410 in the T2DM group was higher than that in the control group [odds ratio (OR) = 1.738, 95% confidence interval (CI) = 1.055-2.865], suggesting that the G allele is a risk factor of T2DM in the Chinese Han population.
|
25501168 |
2014 |