|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
Previous studies have investigated the association of TNF-α-238G/A (rs361525) and -308G/A (rs1800629) polymorphisms with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
|
30916218 |
2019 |
|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
The aim of this study was to determine whether the TNF -1031T/C (rs1799964), -376G/A (rs1800750), -308G/A (rs1800629) -238G/A (rs361525), and TNFR1 -609G/T polymorphisms are associated with RA susceptibility in a sample of Mexican patients.
|
29404828 |
2018 |
|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
This study identifies a potentially important role for TNF-α rs1800629 polymorphisms in the susceptibility to RA.However, further studies in larger cohorts are required.
|
25263964 |
2014 |
|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
TNF-α rs1800629 A/G, NLRP1 rs878329 C/G and NLRP1 rs6502867 C/T polymorphisms were not associated with risk of RA or AS.
|
24065540 |
2013 |
|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
A long-term observational early RA inception cohort (n = 208) with detailed information about disease activity and radiologic damage after 3, 6 and 9 years of disease was genotyped for the TNFA -308G > A promoter polymorphism (rs1800629).
|
23217265 |
2012 |
|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
In this regard, besides a strong association between the HLA-DRB1∗04 shared epitope alleles and both endothelial dysfunction, an early step in the atherosclerotic process, and clinically evident CV disease, other polymorphisms belonging to genes implicated in inflammatory and metabolic pathways, located inside and outside the HLA region, such as the 308 variant (G > A, rs1800629) of the TNFA locus, the rs1801131 polymorphism (A > C; position + 1298) of the MTHFR locus, or a deletion of 32 base pairs on the CCR5 gene, seem to be associated with the risk of CV disease in patients with RA.
|
22927710 |
2012 |
|
rs1800629
|
|
Rheumatoid Arthritis
|
|
0.070 |
GeneticVariation
|
BEFREE |
Our results show that TNFA rs1800629 gene polymorphism is associated with predisposition to CV complications in patients with RA.
|
21420089 |
2011 |
|
rs1800629
|
|
Lymphoma, Non-Hodgkin
|
|
0.060 |
GeneticVariation
|
BEFREE |
In the presence of the rs1800629 AG/AA genotype, B-cell-mediated autoimmune conditions increased NHL risk (OR = 3.27, 95% CI: 2.07, 5.16; P-interaction = 0.03) in comparison with the GG genotype (OR = 1.82, 95% CI: 1.31, 2.53).
|
25713336 |
2015 |
|
rs1800629
|
|
Lymphoma, Non-Hodgkin
|
|
0.060 |
GeneticVariation
|
BEFREE |
Statistically significant interactions with blood transfusion were observed for IL10RA (rs9610) (P(forinteraction) = 0.003) and TNF (rs1800629) (P(forinteraction) = 0.012) for NHL overall and IL10RA (rs9610) (P(forinteraction) = 0.001) and TNF (rs1800629) (P(forinteraction) = 0.019) for B-cell lymphoma.
|
22649007 |
2012 |
|
rs1800629
|
|
Lymphoma, Non-Hodgkin
|
|
0.060 |
GeneticVariation
|
BEFREE |
TNF rs1800629 was associated with risk of NHL (OR 1.53, 95% confidence interval, CI, 1.06-2.19 for minor allele homozygosity), T-cell lymphoma (OR 2.54, CI 1.27-5.09) and mantle cell lymphoma (OR 2.84, CI 1.38-5.87).
|
20087644 |
2010 |
|
rs1800629
|
|
Lymphoma, Non-Hodgkin
|
|
0.060 |
GeneticVariation
|
BEFREE |
Two single nucleotide polymorphisms (SNPs) in adjacent genes, lymphotoxin alpha (LTA +252G, rs909253 A>G) and tumor necrosis factor (TNF -308A, rs1800629 G>A), form the G-A haplotype repeatedly associated with increased risk of non-Hodgkin lymphoma (NHL) in individuals uninfected with HIV-1.
|
19654554 |
2009 |
|
rs1800629
|
|
Lymphoma, Non-Hodgkin
|
|
0.060 |
GeneticVariation
|
BEFREE |
Compared with the wild-type (GG), the AA genotype for the TNF promoter polymorphism G-308A (rs1800629) was associated with increased risk of NHL [odds ratio (OR), 2.14; 95% confidence interval (95% CI), 0.94-4.85], whereas the GA genotype was not (OR, 1.00; 95% CI, 0.74-1.34).
|
18990758 |
2008 |
|
rs1800629
|
|
Lymphoma, Non-Hodgkin
|
|
0.060 |
GeneticVariation
|
BEFREE |
Two common single nucleotide polymorphisms in immunoregulatory genes (TNF G308A, rs1800629 and IL10 T3575A, rs1800890) have been recently reported as risk factors for non-Hodgkin lymphoma (NHL) in a large pooled analysis.
|
17510437 |
2007 |
|
rs1800629
|
|
Malignant tumor of cervix
|
|
0.050 |
GeneticVariation
|
BEFREE |
The rs361525, rs1800629, and rs17999645 were significantly correlated with the diagnosis of cervical cancer.
|
29940817 |
2018 |
|
rs1800629
|
|
cervical cancer
|
|
0.050 |
GeneticVariation
|
BEFREE |
The rs361525, rs1800629, and rs17999645 were significantly correlated with the diagnosis of cervical cancer.
|
29940817 |
2018 |
|
rs1800629
|
|
Cervix carcinoma
|
|
0.050 |
GeneticVariation
|
BEFREE |
The rs361525, rs1800629, and rs17999645 were significantly correlated with the diagnosis of cervical cancer.
|
29940817 |
2018 |
|
rs1800629
|
|
Septicemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
Our results suggest that the G/A genotype of <i>TNF-α</i> rs1800629 and rs361525 increases sepsis risk in an Asian population.
|
29340067 |
2017 |
|
rs1800629
|
|
Malignant tumor of cervix
|
|
0.050 |
GeneticVariation
|
BEFREE |
Published data linking single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-?) promoter region at positions -308G>A (rs1800629) and -238G>A (rs361525) to cervical cancer risk have been inconclusive.
|
27039819 |
2016 |
|
rs1800629
|
|
cervical cancer
|
|
0.050 |
GeneticVariation
|
BEFREE |
Published data linking single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-?) promoter region at positions -308G>A (rs1800629) and -238G>A (rs361525) to cervical cancer risk have been inconclusive.
|
27039819 |
2016 |
|
rs1800629
|
|
Cervix carcinoma
|
|
0.050 |
GeneticVariation
|
BEFREE |
Published data linking single nucleotide polymorphisms (SNPs) in the tumor necrosis factor-alpha (TNF-?) promoter region at positions -308G>A (rs1800629) and -238G>A (rs361525) to cervical cancer risk have been inconclusive.
|
27039819 |
2016 |
|
rs1800629
|
|
Septicemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
We conducted a cross-sectional study to genotype 415 septic patients and 205 patients without sepsis for the SNPs -308(G/A) rs1800629 of TNF; +252 (G/A) rs909253 of LTA; -511(A/G) rs16944 and +3953(C/T) rs1143634 of IL1B; and -1082(A/G) rs1800896, -819(C/T) rs1800871 and -592(C/A) rs1800872 of IL10.
|
27592234 |
2016 |
|
rs1800629
|
|
Septicemia
|
|
0.050 |
GeneticVariation
|
BEFREE |
In the present study, we aim to investigate the association of promoter-region polymorphisms IL-6 (-174G/C) rs1800795 and TNF-α (-308G/A) rs1800629 with pneumonia-induced sepsis.
|
26025100 |
2015 |
|
rs1800629
|
|
cervical cancer
|
|
0.050 |
GeneticVariation
|
BEFREE |
Using high-resolution melting curve analysis, we investigated the prevalence of the TNF-α -308 G/A transition (rs1800629) in patients with cervical cancer (n = 362) and control subjects (n = 399).
|
25614219 |
2015 |
|
rs1800629
|
|
Cervix carcinoma
|
|
0.050 |
GeneticVariation
|
BEFREE |
Using high-resolution melting curve analysis, we investigated the prevalence of the TNF-α -308 G/A transition (rs1800629) in patients with cervical cancer (n = 362) and control subjects (n = 399).
|
25614219 |
2015 |
|
rs1800629
|
|
Malignant tumor of cervix
|
|
0.050 |
GeneticVariation
|
BEFREE |
Using high-resolution melting curve analysis, we investigated the prevalence of the TNF-α -308 G/A transition (rs1800629) in patients with cervical cancer (n = 362) and control subjects (n = 399).
|
25614219 |
2015 |