Source: CURATED

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		A 0.850 GeneticVariation GWASCAT Genetic influences on susceptibility to rheumatoid arthritis in African-Americans. 30423114

2019
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		A 0.850 GeneticVariation GWASCAT High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci. 24532676

2015
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		A 0.850 GeneticVariation GWASCAT Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342

2014
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		A 0.850 GeneticVariation GWASDB Genetics of rheumatoid arthritis contributes to biology and drug discovery. 24390342

2014
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.850 GeneticVariation GWASDB High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0201657
Disease: C-reactive protein measurement
C-reactive protein measurement 		0.800 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584

2019
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0201657
Disease: C-reactive protein measurement
C-reactive protein measurement 		0.800 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291

2013
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0201657
Disease: C-reactive protein measurement
C-reactive protein measurement 		0.800 GeneticVariation GWASDB Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study. 18439548

2008
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0013595
Disease: Eczema
Eczema 		0.710 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0011615
Disease: Dermatitis, Atopic
Dermatitis, Atopic 		C 0.710 GeneticVariation GWASCAT Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. 26482879

2015
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure 		0.700 GeneticVariation GWASCAT Genetic analyses of diverse populations improves discovery for complex traits. 31217584

2019
dbSNP: rs2228145
rs2228145
IL6R
CUI: C2985280
Disease: Blood Protein Measurement
Blood Protein Measurement 		A 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576

2018
dbSNP: rs2228145
rs2228145
IL6R
CUI: C1527304
Disease: Allergic Reaction
Allergic Reaction 		C 0.700 GeneticVariation GWASCAT Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology. 29083406

2017
dbSNP: rs2228145
rs2228145
IL6R
CUI: C1561955
Disease: Fibrinogen, CTCAE
Fibrinogen, CTCAE 		0.700 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291

2013
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0337428
Disease: Fibrinogen assay
Fibrinogen assay 		0.700 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291

2013
dbSNP: rs2228145
rs2228145
IL6R
CUI: C1325327
Disease: fibrinogen activity
fibrinogen activity 		0.700 GeneticVariation GWASDB Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers. 23505291

2013
dbSNP: rs2228145
rs2228145
IL6R
CUI: C1561955
Disease: Fibrinogen, CTCAE
Fibrinogen, CTCAE 		C 0.700 GeneticVariation GWASDB Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. 20031577

2009
dbSNP: rs2228145
rs2228145
IL6R
CUI: C0337428
Disease: Fibrinogen assay
Fibrinogen assay 		C 0.700 GeneticVariation GWASDB Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. 20031577

2009
dbSNP: rs2228145
rs2228145
IL6R
CUI: C1325327
Disease: fibrinogen activity
fibrinogen activity 		C 0.700 GeneticVariation GWASDB Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. 20031577

2009
dbSNP: rs2228145
rs2228145
IL6R
CUI: C3540094
Disease: INTERLEUKIN 6, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS
INTERLEUKIN 6, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 		C 0.700 GeneticVariation CLINVAR

dbSNP: rs2228145
rs2228145
IL6R
CUI: C3553493
Disease: SOLUBLE INTERLEUKIN-6 RECEPTOR, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS
SOLUBLE INTERLEUKIN-6 RECEPTOR, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 		C 0.700 GeneticVariation CLINVAR