|
rs2302254
|
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
Thus, our meta-analysis found rs16949649 associated with increased susceptibility to gynecological cancer and rs2302254 was linked to reduced gastric cancer risk; additional, larger studies are required to confirm these findings.
|
29525404 |
2018 |
|
rs2302254
|
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Thus, our meta-analysis found rs16949649 associated with increased susceptibility to gynecological cancer and rs2302254 was linked to reduced gastric cancer risk; additional, larger studies are required to confirm these findings.
|
29525404 |
2018 |
|
rs2302254
|
|
Primary malignant neoplasm
|
|
0.020 |
GeneticVariation
|
BEFREE |
Once having the endometrial cancer, Taiwan women with variant homozygote CC in rs1694964 were at less risk to have non-endometrioid type, while women with variant homozygote TT in rs2302254 tended to have advanced stage cancer.
|
20599259 |
2010 |
|
rs2302254
|
|
Malignant Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
Once having the endometrial cancer, Taiwan women with variant homozygote CC in rs1694964 were at less risk to have non-endometrioid type, while women with variant homozygote TT in rs2302254 tended to have advanced stage cancer.
|
20599259 |
2010 |
|
rs2302254
|
|
Incontinentia Pigmenti Achromians
|
|
0.010 |
GeneticVariation
|
BEFREE |
Specifically, TT genotype at rs16949649 and CC genotype at rs2302254 are risk factors of IPA.
|
31734851 |
2020 |
|
rs2302254
|
|
Recurrent tumor
|
|
0.010 |
GeneticVariation
|
BEFREE |
TT genotype at rs16949649 and CC genotype at rs2302254 were associated with higher rates of tumors larger than 20 mm, Ki67 LI and tumor recurrence.
|
31734851 |
2020 |
|
rs2302254
|
|
Stomach Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Thus, our meta-analysis found rs16949649 associated with increased susceptibility to gynecological cancer and rs2302254 was linked to reduced gastric cancer risk; additional, larger studies are required to confirm these findings.
|
29525404 |
2018 |
|
rs2302254
|
|
Malignant neoplasm of stomach
|
|
0.010 |
GeneticVariation
|
BEFREE |
Thus, our meta-analysis found rs16949649 associated with increased susceptibility to gynecological cancer and rs2302254 was linked to reduced gastric cancer risk; additional, larger studies are required to confirm these findings.
|
29525404 |
2018 |
|
rs2302254
|
|
Secondary malignant neoplasm of lymph node
|
|
0.010 |
GeneticVariation
|
BEFREE |
Patients carrying TT genotype in rs16949649, AA genotype in rs3760468, TT genotype in rs3760469, CC genotype in rs2302254, and GG genotype in rs34214448 were correlated to greater numbers of lymph node metastases (P = 0.023 in rs16949649; P = 0.015 in rs3760468; P = 0.043 in rs3760469; P = 0.008 in rs2302254; and P = 0.021 in rs34214448, respectively).
|
22903495 |
2012 |
|
rs2302254
|
|
Epithelial ovarian cancer
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our studies suggest that rs16949649 and rs2302254 polymorphisms in the nm23 gene promoter may influence the prognosis of patients with epithelial ovarian cancer.
|
22683585 |
2012 |
|
rs2302254
|
|
Carcinoma, Ovarian Epithelial
|
|
0.010 |
GeneticVariation
|
BEFREE |
Our studies suggest that rs16949649 and rs2302254 polymorphisms in the nm23 gene promoter may influence the prognosis of patients with epithelial ovarian cancer.
|
22683585 |
2012 |
|
rs2302254
|
|
Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
In total, 366 blood samples were collected from 244 healthy women and 122 patients with cervical neoplasia to analyze 3 nm23-H1 gene single-nucleotide polymorphisms (rs34214448, rs16949649, and rs2302254).
|
20601538 |
2010 |
|
rs2302254
|
|
Endometrial Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
Once having the endometrial cancer, Taiwan women with variant homozygote CC in rs1694964 were at less risk to have non-endometrioid type, while women with variant homozygote TT in rs2302254 tended to have advanced stage cancer.
|
20599259 |
2010 |
|
rs2302254
|
|
stage, endometrial carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, a trend of increased risk (OR: 26.67; P=0.01) of advanced stage endometrial cancer (stage III-IV) was observed in patients with TT genotype as compared to those with CC genotype in rs2302254.
|
20599259 |
2010 |
|
rs2302254
|
|
Malignant neoplasm of endometrium
|
|
0.010 |
GeneticVariation
|
BEFREE |
Once having the endometrial cancer, Taiwan women with variant homozygote CC in rs1694964 were at less risk to have non-endometrioid type, while women with variant homozygote TT in rs2302254 tended to have advanced stage cancer.
|
20599259 |
2010 |
|
rs2302254
|
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation
|
BEFREE |
In vitro biochemical analyses showed that minor alleles in rs2302254 and rs3760468, which is in strong linkage disequilibrium with rs16949646, altered nuclear proteins binding capacity and reduced NME1 promoter activity, supporting the results from an association study of these SNPs with breast cancer survival.
|
18676749 |
2008 |
|
rs2302254
|
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation
|
BEFREE |
In vitro biochemical analyses showed that minor alleles in rs2302254 and rs3760468, which is in strong linkage disequilibrium with rs16949646, altered nuclear proteins binding capacity and reduced NME1 promoter activity, supporting the results from an association study of these SNPs with breast cancer survival.
|
18676749 |
2008 |