|
rs2569190
|
|
Periodontitis
|
|
0.030 |
GeneticVariation
|
BEFREE |
Thus, the aim of this study was to evaluate the influence of the <i>TLR4</i> A896G (rs4986790), <i>TLR4</i> C1196T (rs4986791), <i>CD14</i> C-260T (rs2569190), <i>RANKL</i> (<i>TNFSF11</i>, rs2277438), and <i>OPG</i> (<i>TNFSF11B</i> C163T, rs3102735) polymorphisms in periodontitis.
|
31281226 |
2019 |
|
rs2569190
|
|
Periodontitis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The genetic variation in the CD14 rs2569190 promoter region contributes to the susceptibility of developing periodontitis.
|
28829191 |
2017 |
|
rs2569190
|
|
Periodontitis
|
|
0.030 |
GeneticVariation
|
BEFREE |
The CD14/-260 SNP (rs2569190) served as a control, as a recent meta-analysis suggested no relationship between this SNP and periodontitis.
|
26174031 |
2016 |
|
rs2569190
|
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
The SNP rs2569190 significantly contribute to susceptibility and development of cardiovascular disease, particularly in the East Asian population and in the subtype CHD group, in addition, a potential association was observed in the AMI group, T allele acts as a risk factor for cardiovascular disease.
|
30922395 |
2019 |
|
rs2569190
|
|
Septicemia
|
|
0.020 |
GeneticVariation
|
BEFREE |
In conclusion, CD14 rs2569190 may act as a prognostic variable for the short-term outcome (30-day survival) in patients with sepsis.
|
26020644 |
2015 |
|
rs2569190
|
|
Sepsis
|
|
0.020 |
GeneticVariation
|
BEFREE |
In conclusion, CD14 rs2569190 may act as a prognostic variable for the short-term outcome (30-day survival) in patients with sepsis.
|
26020644 |
2015 |
|
rs2569190
|
|
Septicemia
|
|
0.020 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphisms (SNPs) of TLR4 (rs10759932, rs11536889, rs7873784, rs12377632, rs1927907, rs1153879) and CD14 (rs2569190 and rs2563298) in patients with sepsis and control subjects in the Guangxi Province were analyzed by using the polymerase chain reaction-single base extension (PCR-SBE) and DNA sequencing methods.
|
25394369 |
2014 |
|
rs2569190
|
|
Sepsis
|
|
0.020 |
GeneticVariation
|
BEFREE |
The single nucleotide polymorphisms (SNPs) of TLR4 (rs10759932, rs11536889, rs7873784, rs12377632, rs1927907, rs1153879) and CD14 (rs2569190 and rs2563298) in patients with sepsis and control subjects in the Guangxi Province were analyzed by using the polymerase chain reaction-single base extension (PCR-SBE) and DNA sequencing methods.
|
25394369 |
2014 |
|
rs2569190
|
|
Asthma
|
|
0.020 |
GeneticVariation
|
BEFREE |
To investigate associations between total serum immunoglobulin E (IgE) levels and single nucleotide polymorphisms (SNPs) from eight candidate genes (IL-4 rs2243250, IL-4Rα rs1805010, IL-13 rs20541, IL-13Rα1 rs2495636, CD14 rs2569190, tumor necrosis factor-alpha (TNF-α) rs1800629, cytotoxic T lymphocyte-associated antigen (CTLA4) rs231775, FCER1B rs1441585) in children with asthma and to evaluate gene-gene interactions.
|
22376040 |
2012 |
|
rs2569190
|
|
Asthma
|
|
0.020 |
GeneticVariation
|
BEFREE |
The aim of our study was to perform an association analysis of promoter single nucleotide polymorphism (SNP) -159C/T (rs2569190) in the CD14 gene for Slovenian children with asthma.
|
22015088 |
2011 |
|
rs2569190
|
|
Cardiovascular Diseases
|
|
0.020 |
GeneticVariation
|
BEFREE |
The C260T (rs2569190) single-nucleotide polymorphism (SNP) in the promoter region of the CD14 gene was implicated in CVD.
|
19433913 |
2009 |
|
rs2569190
|
|
Malignant Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two polymorphisms, -260 C>T (rs2569190) and -561 C>T (rs5744455), in the CD14 gene have been implicated in susceptibility to cancer.
|
31826310 |
2020 |
|
rs2569190
|
|
Primary malignant neoplasm
|
|
0.010 |
GeneticVariation
|
BEFREE |
Two polymorphisms, -260 C>T (rs2569190) and -561 C>T (rs5744455), in the CD14 gene have been implicated in susceptibility to cancer.
|
31826310 |
2020 |
|
rs2569190
|
|
Myocardial Infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
Numerous published studies have investigated the relationship between the CD14-260C>T (rs2569190) polymorphism and the risk of myocardial infarction (MI).
|
31183977 |
2019 |
|
rs2569190
|
|
Anemia, Sickle Cell
|
|
0.010 |
GeneticVariation
|
BEFREE |
The CD14 (rs2569190) gene promoter demonstrated a significant difference (p < 0.02) between African and African American SCD groups, with the mutant variant (-159 T/T) more frequent (p < 0.0002) in African American SCD (38.9% versus 26.2%).
|
31474499 |
2019 |
|
rs2569190
|
|
Ischemic stroke
|
|
0.010 |
GeneticVariation
|
BEFREE |
The current evidence indicated that <i>CD14</i> rs2569190 C>T polymorphism was not a critical risk factor for IS development.
|
30613146 |
2019 |
|
rs2569190
|
|
IgE-mediated food allergy
|
|
0.010 |
GeneticVariation
|
BEFREE |
Development of FA was associated with longer periods of breastfeeding (adjusted OR = 1.792, P = .03), and this dietary pattern was more significantly related to the development of FA in infants with the homozygous TT genotype of CD14 (rs2569190) and more than 1 copy of GSTM1 and GSTT1.
|
30930272 |
2019 |
|
rs2569190
|
|
Coronary Arteriosclerosis
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of COL4A1 (rs605143, rs565470) and CD14 (rs2569190) genes polymorphism with coronary artery disease.
|
29299748 |
2018 |
|
rs2569190
|
|
Biliary Atresia
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the association of two cis-regulated variants in CD14 (rs2569190) and NOTCH2 (rs835576) with BA susceptibility, using the largest case-control cohort, totaling 506 BA patients and 1,473 healthy controls in a Southern Chinese population.
|
30439647 |
2018 |
|
rs2569190
|
|
Congenital atresia of extrahepatic bile duct
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the association of two cis-regulated variants in CD14 (rs2569190) and NOTCH2 (rs835576) with BA susceptibility, using the largest case-control cohort, totaling 506 BA patients and 1,473 healthy controls in a Southern Chinese population.
|
30439647 |
2018 |
|
rs2569190
|
|
Acute myocardial infarction
|
|
0.010 |
GeneticVariation
|
BEFREE |
To investigate the possible association between CD14 C(-260)T (rs2569190) gene polymorphism and the risk of acute myocardial infarction in the Egyptian population.
|
29874995 |
2018 |
|
rs2569190
|
|
Coronary heart disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
Association of COL4A1 (rs605143, rs565470) and CD14 (rs2569190) genes polymorphism with coronary artery disease.
|
29299748 |
2018 |
|
rs2569190
|
|
Allergic rhinitis (disorder)
|
|
0.010 |
GeneticVariation
|
BEFREE |
However, the accumulating evidence does not support an association of IL-13 SNP rs1800925 and CD14 SNP rs2569190 with AR risk.
|
29687183 |
2018 |
|
rs2569190
|
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In this study, CD14 (rs2569190), CC (P = 0.008) genotypes, and C allele (P = 0.007) were found to be a positive risk factor, while TT genotype (P = 0.045) and T allele (P = 0.007) as negative risk factor for CAD.
|
29299748 |
2018 |
|
rs2569190
|
|
Graves Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
In genetic model analysis, the allele model, recessive model, and homozygous model of rs2569190 and rs2915863 embodied strong correlations with GD after the adjusting of age and gender (<i>P</i> = 0.014, <i>P</i> = 0.015, <i>P</i> = 0.009, and <i>P</i> = 0.014, <i>P</i> = 0.001, <i>P</i> = 0.006, respectively).
|
30700980 |
2018 |