Source: GWASDB

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2736100
rs2736100
TERT
CUI: C0017638
Disease: Glioma
Glioma 		C 0.900 GeneticVariation GWASDB Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 24908248

2014
dbSNP: rs2736100
rs2736100
TERT
CUI: C0017638
Disease: Glioma
Glioma 		G 0.900 GeneticVariation GWASDB Genome-wide association study of glioma and meta-analysis. 22886559

2012
dbSNP: rs2736100
rs2736100
TERT
CUI: C0017638
Disease: Glioma
Glioma 		0.900 GeneticVariation GWASDB Chromosome 7p11.2 (EGFR) variation influences glioma risk. 21531791

2011
dbSNP: rs2736100
rs2736100
TERT
CUI: C0017638
Disease: Glioma
Glioma 		0.900 GeneticVariation GWASDB Combinations of newly confirmed Glioma-Associated loci link regions on chromosomes 1 and 9 to increased disease risk. 21827660

2011
dbSNP: rs2736100
rs2736100
TERT
CUI: C0017638
Disease: Glioma
Glioma 		G 0.900 GeneticVariation GWASDB We identified five risk loci for glioma at 5p15.33 (rs2736100, TERT; P = 1.50 x 10(-17)), 8q24.21 (rs4295627, CCDC26; P = 2.34 x 10(-18)), 9p21.3 (rs4977756, CDKN2A-CDKN2B; P = 7.24 x 10(-15)), 20q13.33 (rs6010620, RTEL1; P = 2.52 x 10(-12)) and 11q23.3 (rs498872, PHLDB1; P = 1.07 x 10(-8)). 19578367

2009
dbSNP: rs2736100
rs2736100
TERT
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.880 GeneticVariation GWASDB A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. 22797724

2012
dbSNP: rs2736100
rs2736100
TERT
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		C 0.880 GeneticVariation GWASDB The combined analyses identified two susceptibility loci for lung adenocarcinoma: TERT (rs2736100, combined P = 2.91 × 10⁻¹¹), odds ratio (OR) = 1.27) and TP63 (rs10937405, combined P = 7.26 × 10⁻¹²), OR = 1.31). 20871597

2010
dbSNP: rs2736100
rs2736100
TERT
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		G 0.880 GeneticVariation GWASDB Since most women in Asia do not smoke, we conducted a genome-wide association study of lung adenocarcinoma in never-smoking females (584 cases, 585 controls) among Han Chinese in Taiwan and found that the most significant association was for rs2736100 on chromosome 5p15.33 (p = 1.30 x 10(-11)). 20700438

2010
dbSNP: rs2736100
rs2736100
TERT
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		G 0.880 GeneticVariation GWASDB A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. 19836008

2009
dbSNP: rs2736100
rs2736100
TERT
CUI: C1800706
Disease: Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis 		A 0.840 GeneticVariation GWASDB A genome-wide association study identifies an association of a common variant in TERT with susceptibility to idiopathic pulmonary fibrosis. 18835860

2008
dbSNP: rs2736100
rs2736100
TERT
CUI: C0206062
Disease: Lung Diseases, Interstitial
Lung Diseases, Interstitial 		A 0.810 GeneticVariation GWASDB Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. 23583980

2013
dbSNP: rs2736100
rs2736100
TERT
CUI: C0085136
Disease: Central Nervous System Neoplasms
Central Nervous System Neoplasms 		C 0.800 GeneticVariation GWASDB Variants near TERT and TERC influencing telomere length are associated with high-grade glioma risk. 24908248

2014
dbSNP: rs2736100
rs2736100
TERT
CUI: C1336708
Disease: Testicular Germ Cell Tumor
Testicular Germ Cell Tumor 		G 0.800 GeneticVariation GWASDB Identification of nine new susceptibility loci for testicular cancer, including variants near DAZL and PRDM14. 23666240

2013
dbSNP: rs2736100
rs2736100
TERT
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		G 0.800 GeneticVariation GWASDB Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. 23143601

2012
dbSNP: rs2736100
rs2736100
TERT
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.800 GeneticVariation GWASDB Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls. 22899653

2012
dbSNP: rs2736100
rs2736100
TERT
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		C 0.800 GeneticVariation GWASDB The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively). 21725308

2011
dbSNP: rs2736100
rs2736100
TERT
CUI: C2931822
Disease: Nasopharyngeal carcinoma
Nasopharyngeal carcinoma 		0.700 GeneticVariation GWASDB A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci. 20512145

2010
dbSNP: rs2736100
rs2736100
TERT
CUI: C0855197
Disease: Malignant Testicular Germ Cell Tumor
Malignant Testicular Germ Cell Tumor 		T 0.700 GeneticVariation GWASDB Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer. 20543847

2010