Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs603965
rs603965
CUI: C0017638
Disease: Glioma
Glioma
0.020 GeneticVariation BEFREE Our findings suggested that CCND1 rs603965 polymorphism may serve as a potential genetic biomarker of brain tumor, especially for glioma. 30972946

2019

dbSNP: rs603965
rs603965
CUI: C0017638
Disease: Glioma
Glioma
0.020 GeneticVariation BEFREE Polymorphism in rs603965 within CCND1 gene and rs1346787 within EFEMP1 gene and its gene- gene interaction were associated with increased glioma risk. 28380465

2017

dbSNP: rs603965
rs603965
CUI: C0025286
Disease: Meningioma
Meningioma
0.010 GeneticVariation BEFREE Moreover, in stratified analyses by type of disease, we noticed that the rs603965 polymorphism was significantly associated with the susceptibility to glioma, but such positive results were not detected in pituitary adenoma or meningioma. 30972946

2019

dbSNP: rs603965
rs603965
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 GeneticVariation BEFREE Additionally, a significant association with tumor grade was also observed for the rs603965 polymorphism in G versus A (allele comparison, p = 0.02, OR = 0.74, 95% CI 0.59-0.95, I<sup>2</sup>  = 26%). 30972946

2019

dbSNP: rs603965
rs603965
CUI: C0006118
Disease: Brain Neoplasms
Brain Neoplasms
0.010 GeneticVariation BEFREE Our findings suggested that CCND1 rs603965 polymorphism may serve as a potential genetic biomarker of brain tumor, especially for glioma. 30972946

2019

dbSNP: rs603965
rs603965
CUI: C0278877
Disease: Adult Meningioma
Adult Meningioma
0.010 GeneticVariation BEFREE Moreover, in stratified analyses by type of disease, we noticed that the rs603965 polymorphism was significantly associated with the susceptibility to glioma, but such positive results were not detected in pituitary adenoma or meningioma. 30972946

2019

dbSNP: rs603965
rs603965
Meningioma, benign, no ICD-O subtype
0.010 GeneticVariation BEFREE Moreover, in stratified analyses by type of disease, we noticed that the rs603965 polymorphism was significantly associated with the susceptibility to glioma, but such positive results were not detected in pituitary adenoma or meningioma. 30972946

2019

dbSNP: rs603965
rs603965
CUI: C0699790
Disease: Colon Carcinoma
Colon Carcinoma
0.010 GeneticVariation BEFREE For the rs603965 polymorphism of the CCND1 gene, we observed a protection effect for the colon cancer location under the dominant model (OR=0.49, P=0.0477). 27755946

2016

dbSNP: rs603965
rs603965
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon
0.010 GeneticVariation BEFREE For the rs603965 polymorphism of the CCND1 gene, we observed a protection effect for the colon cancer location under the dominant model (OR=0.49, P=0.0477). 27755946

2016

dbSNP: rs603965
rs603965
XERODERMA PIGMENTOSUM, COMPLEMENTATION GROUP C
0.010 GeneticVariation BEFREE The aim of this meta-analysis is to generate large-scale evidence to determine the degree to which common Cyclin D1 (CCND1) G870A (dbSNP: rs603965) and xeroderma pigmentosum group C (XPC) Ala499Val (dbSNP: rs2228000) polymorphisms are associated with susceptibility to bladder cancer. 24264314

2014

dbSNP: rs603965
rs603965
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm
0.010 GeneticVariation BEFREE The aim of this meta-analysis is to generate large-scale evidence to determine the degree to which common Cyclin D1 (CCND1) G870A (dbSNP: rs603965) and xeroderma pigmentosum group C (XPC) Ala499Val (dbSNP: rs2228000) polymorphisms are associated with susceptibility to bladder cancer. 24264314

2014

dbSNP: rs603965
rs603965
Malignant neoplasm of urinary bladder
0.010 GeneticVariation BEFREE The aim of this meta-analysis is to generate large-scale evidence to determine the degree to which common Cyclin D1 (CCND1) G870A (dbSNP: rs603965) and xeroderma pigmentosum group C (XPC) Ala499Val (dbSNP: rs2228000) polymorphisms are associated with susceptibility to bladder cancer. 24264314

2014

dbSNP: rs603965
rs603965
CUI: C0699885
Disease: Carcinoma of bladder
Carcinoma of bladder
0.010 GeneticVariation BEFREE The aim of this meta-analysis is to generate large-scale evidence to determine the degree to which common Cyclin D1 (CCND1) G870A (dbSNP: rs603965) and xeroderma pigmentosum group C (XPC) Ala499Val (dbSNP: rs2228000) polymorphisms are associated with susceptibility to bladder cancer. 24264314

2014

dbSNP: rs603965
rs603965
CUI: C0024305
Disease: Lymphoma, Non-Hodgkin
Lymphoma, Non-Hodgkin
0.010 GeneticVariation BEFREE The cyclin D1 (CCND1) splice variant G870A (rs603965) increased NHL risk (OR(AA) = 1.4, 95% CI = 1.1-1.8, P-trend = 0.021), which was consistent for four B-cell subtypes. 16783567

2006