Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms 		0.010 GeneticVariation BEFREE The combined results indicated no association of A453G with cancer risk; however, an association was observed specifically for prostate cancer. 25434509

2015
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma 		0.010 GeneticVariation BEFREE The A453G polymorphism was found to modify the risk of prostate cancer. 25434509

2015
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE The combined results indicated no association of A453G with cancer risk; however, an association was observed specifically for prostate cancer. 25434509

2015
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE The A453G polymorphism was found to modify the risk of prostate cancer. 25434509

2015
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.010 GeneticVariation BEFREE In this meta analysis, we assessed 10 case-control studies included 7,067 cases and 9,374 controls of the association between CYP1B1 SNPs of Leu432Val (rs1056836, 432C>G), Asn453Ser (rs1800440, 453A>G), Ala119Ser (rs1056827, 119G>T), Arg48Gly (rs10012, 48C>G) and the risk of lung cancer. 21674184

2012
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.010 GeneticVariation BEFREE In this meta analysis, we assessed 10 case-control studies included 7,067 cases and 9,374 controls of the association between CYP1B1 SNPs of Leu432Val (rs1056836, 432C>G), Asn453Ser (rs1800440, 453A>G), Ala119Ser (rs1056827, 119G>T), Arg48Gly (rs10012, 48C>G) and the risk of lung cancer. 21674184

2012
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.010 GeneticVariation BEFREE Overall, the variant genotypes (GG and GA) of the 453 A/G were not associated with CRC risk when compared with the wild-type AA homozygote (GG vs AA, OR=0.94, 95% CI=0.77-1.14; GA vs AA, OR=0.99, 95% CI=0.87-1.12). 22459615

2012
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C1306460
Disease: Primary malignant neoplasm of lung
Primary malignant neoplasm of lung 		0.010 GeneticVariation BEFREE In this meta analysis, we assessed 10 case-control studies included 7,067 cases and 9,374 controls of the association between CYP1B1 SNPs of Leu432Val (rs1056836, 432C>G), Asn453Ser (rs1800440, 453A>G), Ala119Ser (rs1056827, 119G>T), Arg48Gly (rs10012, 48C>G) and the risk of lung cancer. 21674184

2012
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0235653
Disease: Malignant neoplasm of female breast
Malignant neoplasm of female breast 		0.010 GeneticVariation BEFREE In this paper, we report findings from a family-based association study examining the association between polymorphisms in two key estrogen-metabolism genes CYP1B1 (codon 432 G --> C and codon 453 A --> G variants) and COMT (codon 158 G --> A variant) and female breast cancer. 15111770

2004
dbSNP: rs760025060
rs760025060
CYP1B1 ; CYP1B1-AS1
CUI: C0007104
Disease: Female Breast Carcinoma
Female Breast Carcinoma 		0.010 GeneticVariation BEFREE In this paper, we report findings from a family-based association study examining the association between polymorphisms in two key estrogen-metabolism genes CYP1B1 (codon 432 G --> C and codon 453 A --> G variants) and COMT (codon 158 G --> A variant) and female breast cancer. 15111770

2004