Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE We found the BDNF Val66Met to be associated with alcohol dependence (p = 0.004). 29357295

2018

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE Haplotype analysis revealed the rs6265-rs7103411 A/C haplotype is associated with comorbid alcohol dependence</span> (P = 0.002). 24993285

2015

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE This study indicates a possible effect of BDNF Val66Met on alcohol addiction-related phenotypes in adolescence. 25650137

2015

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE These results suggest that the BDNF Val66Met polymorphism may contribute to alcohol dependence vulnerability via lower EFs performance. 23582695

2013

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE In conclusion, these data do not support the view that BDNF Val66Met polymorphism correlates with the specific alcohol related phenotypes in ethnically homogenous medication-free Caucasian subjects with alcohol dependence. 23023098

2013

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE An association between the BDNF Val66Met gene polymorphism and alcoholism was not found. 21098877

2011

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE Here, we investigated the possible association between three single nucleotide polymorphisms (SNPs) of the BDNF gene (rs13306221, rs6265, rs16917204) and AD-D. Of 548 patients with alcohol dependence (AD), 166 had AD-D and 312 healthy controls. 21880305

2011

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE The BDNF polymorphism Val66Met (rs6265) has been studied in the context of etiology of mental diseases including alcoholism. 21640793

2011

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE The Val66Met BDNF gene polymorphism was associated with a higher risk and earlier occurrence of relapse among patients treated for alcohol dependence. 19170664

2009

dbSNP: rs6265
rs6265
CUI: C0001973
Disease: Alcoholic Intoxication, Chronic
Alcoholic Intoxication, Chronic
0.100 GeneticVariation BEFREE A study of the association of (Val66Met) polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males. 15896496

2005