|
rs1463038513
|
|
Colonic Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
From this descriptive study, it seems that the short-term risk for colonic polyps in I1307K APC mutation is low, primarily affecting patients with previously diagnosed colon tumors.
|
15733272 |
2005 |
|
rs1463038513
|
|
Colonic Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
We also compared the distribution and frequency of APC mutations from colon tumors that were positive and negative for the I1307K mutation.
|
9869603 |
1999 |
|
rs1801155
|
|
Colonic Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
From this descriptive study, it seems that the short-term risk for colonic polyps in I1307K APC mutation is low, primarily affecting patients with previously diagnosed colon tumors.
|
15733272 |
2005 |
|
rs1801155
|
|
Colonic Neoplasms
|
|
0.020 |
GeneticVariation
|
BEFREE |
We also compared the distribution and frequency of APC mutations from colon tumors that were positive and negative for the I1307K mutation.
|
9869603 |
1999 |
|
rs121913331
|
|
Colonic Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using NGS, the following mutations were detected: nonsense mutations in four tumor suppressor genes [APC R1114X (molecular argument that the cancer was a primary tumor of colon), TP53 R213X, RB1 E137X and FBWX7 R393X & S282X], mutations in three receptor tyrosine kinases (RET A919V of high transforming activity, EGFR E114K and FLT3 L601I) well known as oncogenes.
|
28730258 |
2017 |
|
rs1288422703
|
|
Colonic Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using NGS, the following mutations were detected: nonsense mutations in four tumor suppressor genes [APC R1114X (molecular argument that the cancer was a primary tumor of colon), TP53 R213X, RB1 E137X and FBWX7 R393X & S282X], mutations in three receptor tyrosine kinases (RET A919V of high transforming activity, EGFR E114K and FLT3 L601I) well known as oncogenes.
|
28730258 |
2017 |
|
rs1441008398
|
|
Colonic Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using NGS, the following mutations were detected: nonsense mutations in four tumor suppressor genes [APC R1114X (molecular argument that the cancer was a primary tumor of colon), TP53 R213X, RB1 E137X and FBWX7 R393X & S282X], mutations in three receptor tyrosine kinases (RET A919V of high transforming activity, EGFR E114K and FLT3 L601I) well known as oncogenes.
|
28730258 |
2017 |
|
rs876660427
|
|
Colonic Neoplasms
|
|
0.010 |
GeneticVariation
|
BEFREE |
Using NGS, the following mutations were detected: nonsense mutations in four tumor suppressor genes [APC R1114X (molecular argument that the cancer was a primary tumor of colon), TP53 R213X, RB1 E137X and FBWX7 R393X & S282X], mutations in three receptor tyrosine kinases (RET A919V of high transforming activity, EGFR E114K and FLT3 L601I) well known as oncogenes.
|
28730258 |
2017 |