|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated the gender differences in the effect of ACE I/D and AGT M235T polymorphisms on the prognosis of diabetic nephropathy (DN).
|
18849600 |
2009 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated the relationship of the ACE insertion/deletion (I/D) and AGT M235T</span> gene polymorphisms in Turkish patients with type 2 diabetes mellitus (DM) with and without diabetic nephropathy.
|
18413162 |
2008 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
The impact of polymorphisms in the genes coding for angiotensinogen (M235T), ACE (ID), and angiotensin II type 1 receptor (A(1166)-->C) on decline in GFR and doubling of s-creatinine or development of ESRD in patients with type 1 diabetes and diabetic nephropathy (DN) was tested.
|
14569094 |
2003 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
Conflicting results on the relationship between M235T polymorphism of angiotensinogen (AGT) gene and diabetic nephropathy are reported in the literature, probably due to the small number of subjects, to different inclusion criteria and the different genotype analysis methods used.
|
12270765 |
2002 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
A substitution (M235T) polymorphism in angiotensinogen (AGT) may interact with ACE I/D polymorphism for the risk of diabetic nephropathy, but their prognostic values have to be established by follow-up studies.
|
11181802 |
2001 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our study revealed RAS genes, ACE and AGT-M235T but not AGT-T174M, AGTR1 or REN genotypes, as contributing factors for DN in type 2 diabetes mellitus in Chinese.
|
11776100 |
2000 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
Therefore, we investigated the interaction between long-term glycaemic control and three polymorphisms in the genes coding for AGTR1 (A1166-->C), angiotensin converting enzyme (ACE/ID) and angiotensinogen (M235T) on risk of developing diabetic nephropathy.
|
10907125 |
2000 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
The data do not support a role of ACE (DD/II) or Atg M235T polymorphism in the development of diabetic nephropathy in Chinese patients with type II diabetes, and no synergistic effect was found between them.
|
10352194 |
1999 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
Furthermore, an M235T variant of the angiotensinogen (AGT) gene has been associated with hypertension, an important risk factor for the development and progression of diabetic nephropathy.
|
9049480 |
1997 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggested that ACE I/D polymorphism, but not AGN M235T polymorphism, is a possible genetic risk factor for diabetic nephropathy in Japanese NIDDM patients.
|
8596493 |
1996 |
|
rs1267969615
|
|
Diabetic Nephropathy
|
|
0.100 |
GeneticVariation
|
BEFREE |
We have examined the angiotensin converting enzyme insertion/deletion polymorphism and angiotensinogen methionine 235 threonine polymorphism in a large cohort of Caucasian patients with IDDM and diabetic nephropathy.
|
8877296 |
1996 |