Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4762
rs4762
AGT
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.050 GeneticVariation BEFREE Our study indicated that the T174M polymorphism in the AGT gene was associated with DN in Asians. 30798724

2019
dbSNP: rs4762
rs4762
AGT
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.050 GeneticVariation BEFREE AGT rs699 and rs4762 missense polymorphisms are not associated with DN in our subset of Slovenian T2DM patients. 28488548

2017
dbSNP: rs4762
rs4762
AGT
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.050 GeneticVariation BEFREE Three-locus AGT haplotype analysis (A-6G/T174M/M235T) identified DN-protective (ATM, AMM, GTM) and DN-susceptible (GTM, ATT, GMT and AMT) haplotypes, and demonstrated enrichment of GTT haplotype in macroalbuminuric compared to microalbuminuric or normoalbuminuric patients. 21421655

2011
dbSNP: rs4762
rs4762
AGT
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.050 GeneticVariation BEFREE Our study revealed RAS genes, ACE and AGT-M235T but not AGT-T174M, AGTR1 or REN genotypes, as contributing factors for DN in type 2 diabetes mellitus in Chinese. 11776100

2000
dbSNP: rs4762
rs4762
AGT
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy 		0.050 GeneticVariation BEFREE We conclude that neither the M235T nor the T174M polymorphism in the angiotensinogen gene contributes to genetic susceptibility to diabetic nephropathy in white IDDM patients, whereas the TT genotype of the M235T is associated with elevated blood pressure in patients with diabetic nephropathy. 8593944

1996