Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800796
rs1800796
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE The stratified analysis showed that rs1800796 G allele carriers (GG/CG) were associated with an increased risk of gastric cancer in the following subgroups: age >64 years old (OR<sub>adjusted</sub> = 1.67, 95% CI = 1.17-2.39), female (OR<sub>adjusted</sub> = 1.82, 95% CI = 1.09-3.05), positive for <i>H. pylori</i> infection (OR<sub>adjusted</sub> = 1.54, 95% CI = 1.07-2.22), non-cardiac gastric cancer (OR<sub>adjusted</sub> = 1.53, 95% CI = 1.15-2.04), stage T3-T4 tumor (OR<sub>adjusted</sub> = 1.41, 95% CI = 1.06-1.88), and gastric cancer with median to high differentiation (OR<sub>adjusted</sub> = 1.45, 95% CI = 1.08-1.96). 31312381

2019

dbSNP: rs1800796
rs1800796
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE Furthermore, rs1800796 was significantly associated with increased risk of lung cancer, prostate cancer and colorectal cancer but not gastric cancer. 29552316

2018

dbSNP: rs1800796
rs1800796
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE Further subgroup analyses based on ethnicities of participants revealed that the IL-4 rs2243250, IL-6 rs1800796 and IL-8 rs4073 polymorphisms were significantly associated with the risk of GC in Asians. 30071135

2018

dbSNP: rs1800796
rs1800796
CUI: C0024623
Disease: Malignant neoplasm of stomach
Malignant neoplasm of stomach
0.040 GeneticVariation BEFREE Epidemiological studies have evaluated the associations between interleukin-6 (IL-6) gene -174 C/G (rs1800795) and -572 C/G (rs1800796) polymorphisms and gastric cancer (GC) risk, but results and conclusions remain controversial. 22711691

2012