Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 GeneticVariation BEFREE Therefore, we investigated the role of an Asp299Gly mutation in the TLR-4 receptor in 890 MS patients with multiple sclerosis and 350 healthy controls. 15932772

2005
dbSNP: rs4986790
rs4986790
TLR4
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.020 GeneticVariation BEFREE In this study we determined whether genetic variants of toll-like receptor (TLR) 4, which confer substantial differences in the inflammation elicited by bacterial lipopolysaccharide, are related to the development of MS. We found no differences in the frequencies of the cosegregating TLR4 Asp299Gly and Thr399Ile polymorphisms between Austrian MS patients (11.6%) and age-matched controls (13.7%). 12622779

2003