|
rs34911341
|
|
Obesity
|
|
0.710 |
GeneticVariation
|
BEFREE |
Arg51Gln mutation was associated with lower plasma ghrelin levels but not with obesity.
|
12181387 |
2002 |
|
rs34911341
|
|
Obesity
|
T |
0.710 |
SusceptibilityMutation
|
CLINVAR |
|
|
|
|
rs4684677
|
|
Obesity
|
|
0.710 |
GeneticVariation
|
BEFREE |
Replication of the nominal associations with obesity could not be confirmed in a German genome-wide association (GWA) study for rs4684677 and rs572169 polymorphisms.
|
19165163 |
2009 |
|
rs4684677
|
|
Obesity
|
A |
0.710 |
SusceptibilityMutation
|
CLINVAR |
|
|
|
|
rs696217
|
|
Obesity
|
|
0.050 |
GeneticVariation
|
BEFREE |
Average dietary energy in lunch, rs3782886, and rs696217 were associated with obesity, and rs3782886 was associated with other metabolic abnormalities.
|
27245511 |
2019 |
|
rs696217
|
|
Obesity
|
|
0.050 |
GeneticVariation
|
BEFREE |
Minor homozygotes for five preproghrelin gene polymorphisms, namely, -1500C>G (rs3755777), -1062G>C (rs26311), -994C>T (rs26312) (promoter region), Leu72Met (rs696217) (exon 2), and +3056T>C (rs2075356) (intron 2), had high values of total and visceral fat areas, waist circumference, and BMI, indicating significant correlation of the polymorphisms with obesity and fat metabolism.
|
23257630 |
2013 |
|
rs696217
|
|
Obesity
|
|
0.050 |
GeneticVariation
|
BEFREE |
The Leu72Met (+408C>A) polymorphism of the preproghrelin, has been linked to obesity, insulin resistance and diabetes.
|
22441120 |
2012 |
|
rs696217
|
|
Obesity
|
|
0.050 |
GeneticVariation
|
BEFREE |
The Leu72Met (+408C>A) polymorphic variant of the preproghrelin, the gene for the ghrelin precursor, has been linked to obesity, diabetes and metabolic syndrome.
|
17884032 |
2008 |
|
rs696217
|
|
Obesity
|
|
0.050 |
GeneticVariation
|
BEFREE |
The frequencies of the Leu72Met polymorphism were 29.3% in obese, 32.3% in overweight, and 32.5% in lean Korean children.
|
16459454 |
2005 |
|
rs2075356
|
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
Minor homozygotes for five preproghrelin gene polymorphisms, namely, -1500C>G (rs3755777), -1062G>C (rs26311), -994C>T (rs26312) (promoter region), Leu72Met (rs696217) (exon 2), and +3056T>C (rs2075356) (intron 2), had high values of total and visceral fat areas, waist circumference, and BMI, indicating significant correlation of the polymorphisms with obesity and fat metabolism.
|
23257630 |
2013 |
|
rs26312
|
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
Minor homozygotes for five preproghrelin gene polymorphisms, namely, -1500C>G (rs3755777), -1062G>C (rs26311), -994C>T (rs26312) (promoter region), Leu72Met (rs696217) (exon 2), and +3056T>C (rs2075356) (intron 2), had high values of total and visceral fat areas, waist circumference, and BMI, indicating significant correlation of the polymorphisms with obesity and fat metabolism.
|
23257630 |
2013 |
|
rs26802
|
|
Obesity
|
|
0.010 |
GeneticVariation
|
BEFREE |
Therefore, the present study aimed to evaluate the relationships among the gene polymorphisms ghrelin (GHRL-rs26802), ghrelin receptor (GHSR-rs572169), leptin (LEP-rs7799039), leptin receptor (LEPR-rs1137101) and fat mass and obesity-associated (FTO-rs9939609) and obesity.
|
26255942 |
2015 |