rs1045642
|
|
Parkinson Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
However, the association between the MDR1 polymorphisms (C1236T and C3435T) and its susceptibility to PD is inconclusive.
|
27538645 |
2016 |
rs1045642
|
|
Parkinson Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
The NOS1 exon18 and ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas NOS1 exon29 and ABCB1 3435C/T polymorphisms might not contribute to PD susceptibility.
|
27749554 |
2016 |
rs1045642
|
|
Parkinson Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
In a population-based case control study, we genotyped ABCB1 gene variants at rs1045642 (c.3435C/T) and rs2032582 (c.2677G/T/A) and assessed occupational exposures to organochlorine (OC) and organophosphorus (OP) pesticides based on self-reported occupational use and record-based ambient workplace exposures for 282 PD cases and 514 controls of European ancestry.
|
26457621 |
2015 |
rs1045642
|
|
Parkinson Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
Our results suggest that the C3435T polymorphism may not play an important role in PD susceptibility in Japanese.
|
22971641 |
2013 |
rs1045642
|
|
Parkinson Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
Among 207 cases and 482 matched controls, ABCB1 polymorphisms were not associated with PD (C3435T, P = .43; G2677[A,T], P = .97).
|
20558393 |
2010 |
rs1045642
|
|
Parkinson Disease
|
|
0.060 |
GeneticVariation
|
BEFREE |
The frequency of each individual SNPs; -41 A > G (intron -1), -145 C > G (exon 1), -129 T > C (exon 1), 1236 T > C (exon 12), 2677 G > T/A (exon 21), 3435 C > T (exon 26), and 4036 A > G (exon 28) did not differ between PD and controls.
|
15542248 |
2004 |
rs1128503
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
The NOS1 exon18 and ABCB1 1236C/T variants might play a role in the risk of Parkinson's disease, whereas NOS1 exon29 and ABCB1 3435C/T polymorphisms might not contribute to PD susceptibility.
|
27749554 |
2016 |
rs1128503
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
Overall, the analysis suggested that MDR1 C123</span>6T polymorphism substantially contribute to Parkinson's disease in the recessive genetic model.
|
27538645 |
2016 |
rs1128503
|
|
Parkinson Disease
|
|
0.030 |
GeneticVariation
|
BEFREE |
The frequency of each individual SNPs; -41 A > G (intron -1), -145 C > G (exon 1), -129 T > C (exon 1), 1236 T > C (exon 12), 2677 G > T/A (exon 21), 3435 C > T (exon 26), and 4036 A > G (exon 28) did not differ between PD and controls.
|
15542248 |
2004 |
rs2032582
|
|
Parkinson Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
In a population-based case control study, we genotyped ABCB1 gene variants at rs1045642 (c.3435C/T) and rs2032582 (c.2677G/T/A) and assessed occupational exposures to organochlorine (OC) and organophosphorus (OP) pesticides based on self-reported occupational use and record-based ambient workplace exposures for 282 PD cases and 514 controls of European ancestry.
|
26457621 |
2015 |
rs2032582
|
|
Parkinson Disease
|
|
0.020 |
GeneticVariation
|
BEFREE |
The frequency of each individual SNPs; -41 A > G (intron -1), -145 C > G (exon 1), -129 T > C (exon 1), 1236 T > C (exon 12), 2677 G > T/A (exon 21), 3435 C > T (exon 26), and 4036 A > G (exon 28) did not differ between PD and controls.
|
15542248 |
2004 |
rs1164376164
|
|
Parkinson Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
The frequency of each individual SNPs; -41 A > G (intron -1), -145 C > G (exon 1), -129 T > C (exon 1), 1236 T > C (exon 12), 2677 G > T/A (exon 21), 3435 C > T (exon 26), and 4036 A > G (exon 28) did not differ between PD and controls.
|
15542248 |
2004 |