Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1991517
rs1991517
TSHR ; LOC101928462
CUI: C0154143
Disease: Toxic multinodular goiter
Toxic multinodular goiter 		0.020 GeneticVariation BEFREE The TSHR D727E polymorphism might be involved in the pathogenesis of toxic multinodular goiter (TMNG). 27525921

2016
dbSNP: rs1991517
rs1991517
TSHR ; LOC101928462
CUI: C0154143
Disease: Toxic multinodular goiter
Toxic multinodular goiter 		0.020 GeneticVariation BEFREE This technique was also used to examine peripheral blood genomic DNA from 52 normal individuals and 49 patients with Graves' disease; 33.3% of TMNG (P = 0.019 vs. normal subjects), 16.3% of Graves' disease patients (P = 0.10 vs. normal subjects), and 9.6% of normal individuals were heterozygous for the D727E polymorphism. 10487707

1999