Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs964184
rs964184
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
G 0.810 GeneticVariation GWASCAT A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis). 22399527

2012

dbSNP: rs964184
rs964184
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
G 0.810 GeneticVariation GWASDB A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis). 22399527

2012

dbSNP: rs964184
rs964184
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.810 GeneticVariation BEFREE A previously known lipid locus, APOA1/C3/A4/A5 gene cluster region (SNP rs964184), was associated with MetS in all 4 study samples (P=7.23×10(-9) in meta-analysis). 22399527

2012

dbSNP: rs12286037
rs12286037
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
C 0.800 GeneticVariation GWASCAT A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs12286037
rs12286037
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
C 0.800 GeneticVariation GWASDB A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs2075290
rs2075290
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
C 0.800 GeneticVariation GWASCAT A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs2075290
rs2075290
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
C 0.800 GeneticVariation GWASDB A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs2266788
rs2266788
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
A 0.800 GeneticVariation GWASCAT A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs2266788
rs2266788
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
C 0.800 GeneticVariation GWASDB A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs2266788
rs2266788
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
C 0.800 GeneticVariation GWASCAT A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium. 21386085

2011

dbSNP: rs2075291
rs2075291
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
A 0.720 GeneticVariation GWASCAT Identification of female-specific genetic variants for metabolic syndrome and its component traits to improve the prediction of metabolic syndrome in females. 31170924

2019

dbSNP: rs2075291
rs2075291
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.720 GeneticVariation BEFREE It seems that APOA5 rs2075291 could play an important role in triglyceride and HDL-C level in metabolic syndrome affected, while the association of APOA5 rs662799 polymorphism is still under debate. 26702748

2016

dbSNP: rs2075291
rs2075291
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.720 GeneticVariation BEFREE The chi(2) test and subsequent multivariate logistic regression analysis with adjustment for age, sex and smoking status found that the-3A-->G and 553G-->T (Gly185Cys) polymorphisms of APOA5, the 2052T-->C (Val653Val) and 1866C-->T (Asn591Asn) polymorphisms of LDLR, the 13989A-->G (Ile118Val) polymorphism of CYP3A4 and the 1014T-->A polymorphism of C1QTNF5 were significantly (false discovery rate <0.05) associated with the prevalence of metabolic syndrome, with the variant alleles of APOA5 and C1QTNF5 representing risk factors for and those of LDLR and CYP3A4 being protective against this condition. 17766366

2008

dbSNP: rs6589566
rs6589566
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.710 GeneticVariation GWASCAT Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population. 30382898

2018

dbSNP: rs6589566
rs6589566
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.710 GeneticVariation BEFREE The effects of three constructed haplotypes (TAA, CGG, and CGA, in the order of rs662799, rs651821, and rs6589566) on the TG:HDL-C ratio and MS were estimated using multiple regression analyses in 2,949 Koreans and in each gender separately (1,082 men and 1,867 women). 24618354

2014

dbSNP: rs603446
rs603446
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.700 GeneticVariation GWASCAT Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population. 30382898

2018

dbSNP: rs121917821
rs121917821
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.010 GeneticVariation BEFREE The apolipoprotein A5 Q139X, lipoprotein lipase (LPL) Hinf I, human paraoxonase 1 (PON1) 192Arg/Gln, cholesteryl ester transfer protein (CETP) Taq1B, adiponectin 45T>G and leptin (LEP) 25CAG were genotyped by real-time polymerase chain reaction in participants with and without MetS. 30381540

2018

dbSNP: rs2160669
rs2160669
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.010 GeneticVariation BEFREE Four genetic variants (APOA5_rs651821, EFCAB4B_rs4766165, ZNF259_rs2160669 and APOBEC1_rs10845640) were selected because they increased MetS risk after adjusting for covariates. 31544728

2019

dbSNP: rs7118999
rs7118999
CUI: C0524620
Disease: Metabolic Syndrome X
Metabolic Syndrome X
0.010 GeneticVariation BEFREE We explored the association between two novel single nucleotide polymorphism (SNPs) of BUD13 (rs7118999 and rs10488698) and MetS and its complements. 28659142

2017