rs1859962
|
|
Prostate carcinoma
|
G |
0.770 |
GeneticVariation
|
GWASCAT |
Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.
|
29892016 |
2018 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
For rs1859962 at 17q24, genotype dependent expression was observed for the candidate target gene SOX9 in TMPRSS2:ERG fusion-positive PrCa, which was not evident in TMPRSS2:ERG negative tumors.
|
27798103 |
2016 |
rs1859962
|
|
Prostate carcinoma
|
G |
0.770 |
GeneticVariation
|
GWASCAT |
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences.
|
26034056 |
2015 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
We observed no association of the SNPs and the risk of developing PCa (OR 0.84, 95 % CI 0.30-2.38, p = 1.0 to rs1859962 and OR 1.94, 95 % CI 0.57-6.52, p = 0.28 to rs4430796), both sporadic and hereditary.
|
24627192 |
2014 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
Genotype TG on 11q13 (rs7931342, T) could be related to an increased Gleason score, AG on HNF1B (rs4430796, A) could be associated with PSA increase, and TG on 17q24 (rs1859962, G) could be negatively associated with an increased BMI in Chinese men with PCa.
|
23464444 |
2012 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
This identifies a PCa-specific enhancer within the rs1859962 risk LD block that establishes a 1-Mb chromatin loop with the SOX9 gene.
|
22665440 |
2012 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
Furthermore, the SNPs rs6983561 and rs4430796 were associated with a susceptibility to aggressive prostate cancer, whereas rs1859962 was associated with non-aggressive prostate cancer.
|
21557267 |
2011 |
rs1859962
|
|
Prostate carcinoma
|
G |
0.770 |
GeneticVariation
|
GWASCAT |
Genome-wide association study identifies new prostate cancer susceptibility loci.
|
21743057 |
2011 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
Our results show that polymorphism of the G allele of SNP rs1859962 is associated with the risk of prostate cancer in a Chinese population.
|
21959049 |
2011 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
BEFREE |
Recent studies have identified 2 distinct genetic variants along chromosome 17, including allele T of single nucleotide polymorphism rs4430796 on 17q12 and allele G of single nucleotide polymorphism rs1859962 on 17q24, that have been linked to prostate cancer risk.
|
19371897 |
2009 |
rs1859962
|
|
Prostate carcinoma
|
|
0.770 |
GeneticVariation
|
GWASCAT |
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study.
|
19767753 |
2009 |
rs1859962
|
|
Prostate carcinoma
|
G |
0.770 |
GeneticVariation
|
GWASCAT |
Multiple newly identified loci associated with prostate cancer susceptibility.
|
18264097 |
2008 |
rs1859962
|
|
Prostate carcinoma
|
G |
0.770 |
GeneticVariation
|
GWASCAT |
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.
|
17603485 |
2007 |