DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Carcinoma of lung ×

Variant: rs1057519720 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib.

24035431

2013

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer.

23833300

2013

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.

22649091

2012

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations.

21483012

2011

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines.

19238210

2009

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Genetic predictors of MEK dependence in non-small cell lung cancer.

19010912

2008

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

BRAF and RAS mutations in human lung cancer and melanoma.

12460918

2002

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Missense mutations of the BRAF gene in human lung adenocarcinoma.

12460919

2002

dbSNP:

rs1057519720

BRAF

CUI:	C0684249
Disease:	Carcinoma of lung

Carcinoma of lung

0.700

CausalMutation

CLINVAR

Mutations of the BRAF gene in human cancer.

12068308

2002