Source: ALL

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519697
rs1057519697
ALK
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE Alectinib was more effective than crizotinib in inhibiting <i>ALK</i> F1174C-expressing cell growth.<b>Conclusions:</b> These findings implicate <i>ALK</i>-activating mutations in SCCP pathogenesis and suggest the therapeutic potential of targeting <i>ALK</i> molecular alterations in some patients with SCCP.<i>Clin Cancer Res; 24(12); 2732-9.©2018 AACR</i>. 29559559

2018