|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Functional Evaluation of Nine Missense-Type Variants of the Human DNA Glycosylase Enzyme MUTYH in the Japanese Population.
|
26694661 |
2016 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia coli Strain.
|
25820570 |
2015 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Risk of colorectal cancer for carriers of mutations in MUTYH, with and without a family history of cancer.
|
24444654 |
2014 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
MUTYH-associated polyposis (MAP): evidence for the origin of the common European mutations p.Tyr179Cys and p.Gly396Asp by founder events.
|
23361220 |
2014 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.
|
24728327 |
2014 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Loss of MUTYH function in human cells leads to accumulation of oxidative damage and genetic instability.
|
23108399 |
2013 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Germline Mutations in the Polyposis-Associated Genes BMPR1A, SMAD4, PTEN, MUTYH and GREM1 Are Not Common in Individuals with Serrated Polyposis Syndrome.
|
23805267 |
2013 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Colorectal cancer in a monoallelic MYH mutation carrier.
|
23625202 |
2013 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Personalized genomic disease risk of volunteers.
|
24082139 |
2013 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Cancer-associated variants and a common polymorphism of MUTYH exhibit reduced repair of oxidative DNA damage using a GFP-based assay in mammalian cells.
|
22926731 |
2012 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Secondary variants in individuals undergoing exome sequencing: screening of 572 individuals identifies high-penetrance mutations in cancer-susceptibility genes.
|
22703879 |
2012 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
MUTYH-associated colon disease: adenomatous polyposis is only one of the possible phenotypes. A family report and literature review.
|
22158503 |
2012 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
High prevalence of the c.1227_1228dup (p.Glu410GlyfsX43) mutation in Tunisian families affected with MUTYH-associated-polyposis.
|
22744763 |
2012 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
MUTYH gene expression and alternative splicing in controls and polyposis patients.
|
22473953 |
2012 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
MutYH mutation carriers have increased breast cancer risk.
|
21952991 |
2012 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Cancer risks for monoallelic MUTYH mutation carriers with a family history of colorectal cancer.
|
21171015 |
2011 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.
|
20418187 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.
|
19953527 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Biallelic MYH germline mutations as cause of Muir-Torre syndrome.
|
19998059 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Functional analysis of MUTYH mutated proteins associated with familial adenomatous polyposis.
|
20418187 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
|
0.800 |
GeneticVariation
|
UNIPROT |
MUTYH mutations associated with familial adenomatous polyposis: functional characterization by a mammalian cell-based assay.
|
19953527 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Rectum-sparing surgery may be appropriate for biallelic MutYH-associated polyposis.
|
21178863 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
A large-scale meta-analysis to refine colorectal cancer risk estimates associated with MUTYH variants.
|
21063410 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
|
0.800 |
GeneticVariation
|
UNIPROT |
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
|
20848659 |
2010 |
|
rs36053993
|
|
Colorectal Adenomatous Polyposis, Autosomal Recessive
|
T |
0.800 |
CausalMutation
|
CLINVAR |
Adenine DNA glycosylase activity of 14 human MutY homolog (MUTYH) variant proteins found in patients with colorectal polyposis and cancer.
|
20848659 |
2010 |