|
rs11591147
|
|
Coronary Artery Disease
|
|
0.730 |
GeneticVariation
|
BEFREE |
Aim was to estimate the genotypic distribution and risk allele frequencies of 13 Coronary Artery Disease (CAD) risk Single Nucleotide Polymorphisms in loci identified by the CARDIoGRAMplusC4D consortium namely MIA3 rs17465637; 9p21 rs10757274; CXCL12 rs1746048; APOA5 rs662799; APOB rs1042031; LPA rs3798220; LPA 10455872; MRAS rs9818870; LPL rs328; SORT1 rs646776; PCSK9 rs11591147; APOE rs429358; APOE rs7412 in Pakistani PCAD patients and controls.
|
28705542 |
2019 |
|
rs11591147
|
|
Coronary Artery Disease
|
T |
0.730 |
GeneticVariation
|
GWASCAT |
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
|
30104761 |
2018 |
|
rs11591147
|
|
Coronary Artery Disease
|
T |
0.730 |
GeneticVariation
|
GWASCAT |
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
|
29212778 |
2018 |
|
rs11591147
|
|
Coronary Artery Disease
|
G |
0.730 |
GeneticVariation
|
GWASCAT |
Association analyses based on false discovery rate implicate new loci for coronary artery disease.
|
28714975 |
2017 |
|
rs11591147
|
|
Coronary Artery Disease
|
|
0.730 |
GeneticVariation
|
BEFREE |
The single-nucleotide polymorphism (SNP) rs11591147 has been associated with lower LDL-cholesterol and a lower risk of coronary heart disease.
|
23300213 |
2013 |
|
rs11591147
|
|
Coronary Artery Disease
|
|
0.730 |
GeneticVariation
|
BEFREE |
The R46L variant in the proprotein-convertase subtilisin-kexin type 9 (PCSK9) gene was associated with reduced levels of LDL and total cholesterol and with a lower risk of coronary artery disease.
|
20699424 |
2010 |
|
rs505151
|
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
In CAD patients, the AG genotype of PSCK9 rs505151 is associated with diabetes and a positive family history of CAD.
|
30947598 |
2020 |
|
rs505151
|
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
No significant association between the PCSK9 E670G polymorphism and serum PCSK9 levels was observed in the CAD group and the controls.
|
30205809 |
2018 |
|
rs505151
|
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
The present meta-analysis concluded that PCSK9 E670G polymorphism was associated with CAD risk and lipid levels.
|
26576960 |
2015 |
|
rs505151
|
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
The E670G polymorphism of the PCSK9 gene is mainly associated with a increased risk and severity of CAD and IS in Tunisian cohort.
|
24599757 |
2014 |
|
rs505151
|
|
Coronary Artery Disease
|
|
0.050 |
GeneticVariation
|
BEFREE |
These results indicate that the E670G polymorphism of the PCSK9 gene modulates plasma LDL-C levels, but that it is not a risk variant for CAD in ethnic Chinese in Taiwan.
|
19191720 |
2009 |
|
rs72555377
|
|
Coronary Artery Disease
|
|
0.010 |
GeneticVariation
|
BEFREE |
We investigated the effect of two known alleles for rs72555377, L10 and L11, on the risk of CAD in a Tunisian cohort (218 patients diagnosed by angiography and 125 control subjects).
|
25239117 |
2015 |