Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11218343
rs11218343
SORL1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.830 GeneticVariation BEFREE We found two SNPs that had interactions with triglycerides on AD risk that reached a p-value < 0.05 (rs11218343 and APOEɛ4). 30412497

2018
dbSNP: rs11218343
rs11218343
SORL1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.830 GeneticVariation BEFREE The results of meta-analysis in subgroups (Caucasian and Asian) and the whole showed that the minor allele (C allele) within rs11218343 played a protective effect on AD risk (OR (95 % CI), 0.77 (0.72-0.83), 0.85 (0.79-0.91), 0.81 (0.76-0.85), respectively). 26873856

2017
dbSNP: rs11218343
rs11218343
SORL1
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.830 GeneticVariation BEFREE Altogether, five loci (rs6656401 at CR1, rs983392within MS4A6A, rs11218343 at SORL1, rs6733839 at BIN1, and APOE ε4) have been detected to be associated with one or a few established AD-related neuroimaging measures. 26732597

2017