|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
We have previously found association between the ABCB1 C-rs3789243-T polymorphism and CRC risk and interactions between the ABCB1 C-rs3789243-T and C3435T polymorphisms and meat intake in relation to CRC risk (Andersen, BMC Cancer, 2009, 9, 407).
|
23977225 |
2013 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
The C3435T polymorphism of the MDR1 gene may influence the transport and excretion of carcinogens, increasing the risk of cancer.
|
22641402 |
2012 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
The results suggested that the MDR1 C3435T polymorphism may contribute to cancer risk.
|
22311042 |
2012 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
In summary, this meta-analysis suggests that the MDR1 C3435T polymorphism is associated with cancer susceptibility, increasing the risk of breast and renal cancer.
|
22358302 |
2012 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
We therefore investigated the influence of polymorphisms G1199A, C1236T, G2677T/A and C3435T on cancer susceptibility, in vitro cytotoxicity and overall survival in 100 de novo AML patients with normal karyotype.
|
20938465 |
2012 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Polymorphism ABCB1 (3435C>T) may be a prediction marker of cancer chemotherapy effectiveness.
|
19415305 |
2009 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
The importance of MDR1 SNPs 2677G > T/A in exon 21 and 3435C > T in exon 26 for cancer susceptibility, however, has not yet been clearly defined.
|
17146660 |
2007 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study investigates the association between ABCB1 gene polymorphism at exon 26 (3435C>T) and risk to UADT cancers in Tamilians, a population of south India.
|
17885624 |
2007 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
We investigated the incidence of C3435T polymorphisms at exon 26 in the MDR-1 gene in 92 women with breast cancer and potential association of altered genotypes with smoking and high body mass index in cancer development among patients.
|
17549370 |
2007 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
Recently, association between the MDR1 C3435T polymorphism and the cancer susceptibility was shown.
|
17300681 |
2007 |
|
rs1045642
|
|
Malignant Neoplasms
|
|
0.100 |
GeneticVariation
|
BEFREE |
These results suggest that ABCB1 3435C>T polymorphism is associated with antiemetic treatment efficacy in patients with cancer treated with 5-HT(3) antagonists, particularly in granisetron-treated patients, during the short-term phase of chemotherapy.
|
16338277 |
2005 |