Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2106809
rs2106809
ACE2
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.020 GeneticVariation BEFREE The circulating ACE2 and Ang-(1-7) levels were related to neither rs4646155 nor rs879922 in female or male patients.In conclusion, the rs2106809 polymorphism of the ACE2 gene may be a determinant of the circulating Ang-(1-7) level in female patients with hypertension, suggesting a genetic association between circulating Ang-(1-7) levels and ACE2 gene polymorphisms in patients with hypertension. 27310975

2016
dbSNP: rs2106809
rs2106809
ACE2
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.020 GeneticVariation BEFREE ACE2 rs2106809 T allele was found to confer a 1.6-fold risk for hypertension in women (95% confidence interval (CI), 1.132.06), whereas when combined with the effect of the ACE DD genotype, the risk was 2.34-fold (95% CI, 1.754.85) in two independent samples. 17473847

2007