Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5273
rs5273
PTGS2
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.010 GeneticVariation BEFREE Prostaglandin H synthase 2 variant (Val511Ala) in African Americans may reduce the risk for colorectal neoplasia. 12433707

2002
dbSNP: rs689466
rs689466
PTGS2 ; PACERR
CUI: C0027651
Disease: Neoplasms
Neoplasms 		0.010 GeneticVariation BEFREE Likewise, the haplotype *4, which contains variant rs689466, was associated with shorter disease-free survival among obese patients (HR<sub>adj</sub> = 3.3; 95% CI = 1.8-6.0), either in luminal (HR<sub>adj</sub> = 3.5; 95% CI = 1.6-7.3) or HER2-like and triple-negative (HR<sub>adj</sub> = 3.1; 95% CI = 1.1-8.9) tumors. 29321183

2018