Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE GpIIIa 1565T/C and homozygous MTHFR 677C/T polymorphisms were higher in DVT patients compared with the control group (OR=6.65, 95% CI=3.09-14.30 and OR=4.08, 95% CI=1.35-12.38, respectively). 26261166

2015

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE The homozygous 20209C>T mutation and the presence of the mutation 677C>T in heterozygosity explained the patient's deep vein thrombosis because the combination of mutations would increase the risk of thrombosis. 24627725

2014

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE The aim of present study was to investigate the prevalence of factor V Leiden (FVL) c.1691G>A, prothrombin g.20210G>A and methylenetetrahydrofolate reductase (MTHFR) c.677C>T in deep vein thrombosis (DVT) patients and their possible association with DVT in western Iran. 20479641

2010

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE Patients with homozygous or combined heterozygous status of MTHFR C677T and A1298C mutation had a higher frequency of DVT after elective THA (odds ratio, 2.86; 95% confidence interval, 1.32-6.35) than those with wild-type. 18800213

2009

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE We studied prothrombotic determinants, namely protein C, protein S, and AT along with factor V Leiden (1691G-->A), prothrombin gene mutation (20210G-->A), CBS 844ins68 mutation, and MTHFR mutation (677C-->T) in consecutive ethnic Omani patients with first episode of a thrombophilic event, namely, deep vein thrombosis (DVT), and/or pulmonary embolism (PE) or thrombosis at an unusual site. 16432849

2006

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE This indicates that FV-Leiden and PRT G20210A, more than MTHFR C677T, are important risk factors for DVT, and that the presence of more than one prothrombotic SNPs was associated with a significant risk of DVT. 16082606

2005

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE We investigated the prevalence of MTHFR C677T and prothrombin G20210A genotypes by polymerase chain reaction (PCR) followed by restriction enzyme digestion in 420 Chinese subjects: 53 with deep venous thrombosis (DVT); 145 with cerebrovascular disease [115 cerebral infarction, 30 cerebral haemorrhage (CH)]; 100 with coronary artery disease (CAD); and 122 control subjects. 10929044

2000

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE MTHFR gene C677T mutation does not increase risk of DVT in BD either alone or combined with FV Leiden mutation. 11128675

2000

dbSNP: rs1188383936
rs1188383936
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE We calculated the prevalences of prothrombin G20210A, factor V G1691A (also associated with high risk for DVT) and homozygous methylenetetrahydrofolate reductase (MTHFR) C677T (associated with increased susceptibility to develop hyperhomocysteinemia) in 118 patients with a first episode of DVT and in 416 healthy controls. 10065893

1999