Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE Coagulation factor V gene 1691G>A polymorphism as an indicator for risk and prognosis of lower extremity deep venous thrombosis in Chinese Han population. 29851809

2018

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE To determine if the deep vein thrombosis was of genetic origin, a peripheral blood DNA sample was analysed for the presence of the three most frequent mutations associated with thrombotic events: factor V Leiden (1691G>A), prothrombin (20210G>A) and methylene tetrahydrofolate reductase (677C>T). 24627725

2014

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE The aim of present study was to investigate the prevalence of factor V Leiden (FVL) c.1691G>A, prothrombin g.20210G>A and methylenetetrahydrofolate reductase (MTHFR) c.677C>T in deep vein thrombosis (DVT) patients and their possible association with DVT in western Iran. 20479641

2010

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE Insofar as the inherited prothrombotic single nucleotide polymorphisms (SNPs) factor V G1691A (FV-Leiden), prothrombin (PRT) G20210A, and methylenetetrahydrofolate reductase (MTHFR), C677T are inherited risk factors of venous thromboembolism (VTE), the aim of this study was to determine the prevalence of single and combined SNPs in 198 patients with documented deep venous thrombosis (DVT), and 697 control subjects, and to estimate the associated risks. 16082606

2005

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE Time from start of chemotherapy infusion to DVT was not significantly different between patients with (median 31 days) and without (median 43 days) G1691A factor V mutation (P = 0.6). 15033664

2004

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE Possible roles of methylenetetrahydrofolate reductase (MTHFR) gene C677T, factor V (FV) gene G1691A (Leiden), and prothrombin gene G20210A polymorphisms in venous thrombogenesis were evaluated in patients with BD; 100 healthy people, 30 BD patients without DVT, 30 BD patients with DVT, and 30 patients with idiopathic DVT were studied with the restriction fragment length polymorphism method for these 3 polymorphisms. 11128675

2000

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE We investigated the prevalence of a genetic variation in the factor V gene (G1691A Leiden mutation) and the prothrombin gene (G20210A) using polymerase chain reaction techniques in samples from 500 normal Thai population and among 50 unselected Thai patients with an objectively confirmed history of deep venous thrombosis. 10996828

2000

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE In contrast, the frequency of the factor V G1691A mutation was similar in subjects with portal vein thrombosis and in controls but was increased in patients with deep vein thrombosis (P = 0.0001). 9869612

1999

dbSNP: rs899127658
rs899127658
F2
CUI: C0149871
Disease: Deep Vein Thrombosis
Deep Vein Thrombosis
0.090 GeneticVariation BEFREE The G20210A mutation of the prothrombin gene in patients with previous first episodes of deep-vein thrombosis: prevalence and association with factor V G1691A, methylenetetrahydrofolate reductase C677T and plasma prothrombin levels. 10065893

1999