|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
We also evaluated patient genotype in the caffeine metabolism related single nucleotide polymorphism rs762551.
|
30179617 |
2019 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
In stratified analysis, a statistical significance within the caffeinated group was observed for the change in systolic BP in the stratum of CYP1A2 polymorphism with daily caffeine consumption ≤90 mg/day: change in systolic BP in the CYP1A2 rs762551 CC group (mean ± SD = 11.8 ± 5.9) was higher than that in the AA/CA group (4.1 ± 5.5).
|
30773300 |
2019 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Spot urine samples obtained 6 hours following 200-mg caffeine administration were used to determine caffeine metabolite ratios (CMRs); blood samples were used to determine CYP1A2*1F (rs762551) and CYP1A2*1C (rs2069514) polymorphisms and the hormonal profile (estradiol, progesterone, and luteinizing and follicle-stimulating hormones) at EFP, LFP, and LP.
|
30591530 |
2019 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
This study aimed to examine whether functional single nucleotide polymorphisms (SNPs) in 1976T > C (ADORA2A; rs5751876) and -163C > A (CYP1A2; rs762551) influence the effect of caffeine on the postprandial glucose (GLU) response to a carbohydrate meal.
|
31324842 |
2019 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Participants were measured twice in a metabolic chamber for a day, four weeks apart, with outcomes including 22 h EE (8:30-6:30), substrate utilization from the respiratory quotient (RQ), plasma caffeine levels (16:00), and genotyping for the single-nucleotide polymorphism (SNP) rs762551.
|
31694152 |
2019 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Our findings do not support the hypothesis of an interaction between the GRIN2A-rs4998386 or CYP1A2-rs762551 polymorphism and caffeine intake in determining PD risk.
|
29318639 |
2018 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
Specifically, the rs762551 SNP in the CYP1A2 gene has been demonstrated to influence caffeine metabolism, with carriers of the C allele considered to be of a 'slow' metaboliser phenotype.
|
29569539 |
2018 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The effects of caffeine on basketball performance were established according to players' CYP1A2 genotype (rs762551): AA homozygotes (n = 10) and C-allele carriers (n = 9).
|
29668752 |
2018 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The association between the single nucleotide polymorphism rs762551 in the cytochrome P450 family 1, subfamily A2 gene (CYP1A2) and caffeine consumption remains controversial.
|
27173183 |
2016 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
The observed increased risk of PD among female but not male carriers of the rs762551 polymorphism of CYP1A2 and the interactions of caffeine with ESR1 rs3798577 and ESR2 rs1255998 may provide clues to explain the relationship between gender, caffeine intake, estrogen status and risk of PD and need to be replicated.
|
20304699 |
2010 |
|
rs762551
|
|
Caffeine related disorders
|
|
0.100 |
GeneticVariation
|
BEFREE |
We collected information on lifetime coffee drinking and we studied two genes: ADORA2A, which encodes the major receptor activity of caffeine in the brain (variants rs5751876 and rs3032740), and CYP1A2, which encodes the major rate-limiting step of caffeine metabolism (variants rs35694136 and rs762551).
|
18759349 |
2008 |