Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE The frequencies of Intron 4 VNTR a/a allele and Glu298Asp GT allele were associated with severe ED, while a/b and TT were associated with moderate or mild, and b/b and GG were associated with no ED. 30977424

2019

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE The G894T and T786C polymorphisms showed a significant association with ED risk in Caucasians (GT + TT versus GG for G894T: OR = 2.13, 95% CI = 1.08-4.19; CC versus CT + TT for T786C: OR = 3.29, 95% CI = 2.30-4.72) and Asians (GT + TT versus GG for G894T: OR = 2.08, 95% CI = 1.53-2.84; CC + CT versus TT for T786C: OR = 3.13, 95% CI = 1.35-7.25). 29654965

2018

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE Our meta-analysis showed that the two single nucleotide polymorphisms in eNOS gene, G894T</span> and T-786C, are strongly associated with the risk of erectile dysfunction. 26908069

2018

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE An increased risk for earlier onset of ED was observed in the G894T risk genotype carriers (odds ratio = 3.572; P < .020). 28268155

2017

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE The eNOS polymorphisms G894T, 4 VNTR, and T786C were associated with an increased risk for ED. 25940782

2015

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE Our investigations demonstrate that eNOS G894T polymorphism might protect men against ED</span> risk. 25726156

2015

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE We studied 118 patients; 63 patients had ED secondary to radical prostatectomy (PED) and 55 had organic, clinical ED. eNOS genotypes for three eNOS polymorphisms (T(-786)C, rs2070744; a variable number of tandem repeats (VNTR) in intron 4; and Glu298Asp, rs1799983) were determined, and eNOS haplotypes were estimated using PHASE 2.1. 22064666

2013

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE The association of eNOS G894T polymorphism with metabolic syndrome and erectile dysfunction. 22304542

2012

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE The result supports that G894T variant is associated with an increase in the risk of ED. 20722785

2010

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE To evaluate a potential association between the G894T polymorphism in the eNOS gene and ED complaints in a population-based sample in São Paulo, Brazil. 19968769

2010

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE The eNOS 894T allele carriers had significantly higher frequencies of ED and higher IPSS, suggesting that eNOS G894T gene polymorphisms may play an implication as a genetic susceptibility factor for both ED and BPH/LUTS. 19515207

2009

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE Logistic regression analysis showed that G894T polymorphism was an independent risk factor for ED. 19473288

2009

dbSNP: rs1799983
rs1799983
CUI: C0242350
Disease: Erectile dysfunction
Erectile dysfunction
0.100 GeneticVariation BEFREE ACE gene I/D and NOS3 G894T polymorphisms and response to sildenafil in men with erectile dysfunction. 12837457

2003