Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11549465
rs11549465
HIF1A ; HIF1A-AS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.060 GeneticVariation BEFREE Our findings indicate that HIF1A rs11549465 polymorphism may not independently play a significant role in the occurrence of prostate cancer. 28415653

2017
dbSNP: rs11549465
rs11549465
HIF1A ; HIF1A-AS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.060 GeneticVariation BEFREE The HIF1A +1772 C>T (rs11549465) polymorphism was genotyped, using DNA isolated from peripheral blood, in 1490 male subjects (754 with prostate cancer and 736 controls cancer-free) through Real-Time PCR. 24090974

2014
dbSNP: rs11549465
rs11549465
HIF1A ; HIF1A-AS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.060 GeneticVariation BEFREE The current findings suggest that HIF1A P582S polymorphism correlates with urinary cancers risk in Caucasian population, while A588T polymorphism may increase the risk of urinary cancers in Asian population and prostate cancer. 23723982

2013
dbSNP: rs11549465
rs11549465
HIF1A ; HIF1A-AS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.060 GeneticVariation BEFREE No altered PCa risk was associated with the rs11549465 and rs2057482 polymorphism. 23042446

2012
dbSNP: rs11549465
rs11549465
HIF1A ; HIF1A-AS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.060 GeneticVariation BEFREE In previous studies, the C1772T (P582S) or the G1790A (A588T) polymorphisms of the HIF-1alpha gene have been identified in renal cell carcinoma, head and neck and esophageal squamous cell carcinomas as well as colorectal and prostate cancers. 18949419

2008
dbSNP: rs11549465
rs11549465
HIF1A ; HIF1A-AS3
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.060 GeneticVariation BEFREE Our data suggest that homozygous HIF1A P582S mutation confers significant susceptibility to prostate cancer. 16998808

2007