Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2234693
rs2234693
ESR1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.050 GeneticVariation BEFREE Studies on the association between two single nucleotide polymorphisms (SNPs) in estrogen receptor α (ERα), PvuII (rs2234693 T>C) and XbaI (rs9340799 A>G), and the prostate cancer risk are inconsistent. 28721070

2017
dbSNP: rs2234693
rs2234693
ESR1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.050 GeneticVariation BEFREE The meta-analysis indicated that ESRα rs9340799 and rs2234693 might contribute to susceptibility and development of PC in European population. 29254246

2017
dbSNP: rs2234693
rs2234693
ESR1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.050 GeneticVariation BEFREE However, there was no significant association between ESR1 rs2234693 and PCa risk. 26251204

2015
dbSNP: rs2234693
rs2234693
ESR1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.050 GeneticVariation BEFREE Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: evidence for association with risk and histopathological tumor characteristics in Iranian men. 22228197

2012
dbSNP: rs2234693
rs2234693
ESR1
CUI: C0376358
Disease: Malignant neoplasm of prostate
Malignant neoplasm of prostate 		0.050 GeneticVariation BEFREE These data suggested that variant rs9340799, but not rs2234693, on ESR1 confers an elevated risk of prostate cancer. 23098495

2012