DisGeNET - a database of gene-disease associations

Source: BEFREE

Disease: Breast Carcinoma ×

Variant: rs587781433 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs587781433

rs587781433

TP53

CUI:	C0678222
Disease:	Breast Carcinoma

Breast Carcinoma

0.010

GeneticVariation

BEFREE

Breast cancer-derived T58A MYC mutations are unable to activate Bim due to their failure to regulate p14/p21.

2019