|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
However, there is no significant association between SNPs variants and cancer risk under any five genetic models for rs4759314, rs1899663 and rs874945.
|
30941992 |
2019 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
However, no significant association was found between the rs1899663, rs874945, and rs4759314 polymorphisms and susceptibility of cancer.
|
29463216 |
2018 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
The results showed that cancer risk was elevated in recessive mutation of rs12826786 (TT vs CC+CT: OR =1.55, 95% CI =1.19, 2.03; TT+CT vs CC: OR =1.23, 95% CI =1.04, 1.46; TT vs CC: OR =1.67, 95% CI =1.24, 2.24; T vs C: OR =1.24, 95% CI =1.09, 1.40) and rs920778 (TT vs CC+CT: OR =1.73, 95% CI =1.30, 2.30; TT+CT vs CC: OR =1.40, 95% CI =1.16, 1.70; TT vs CC: OR =1.83, 95% CI =1.25, 2.68; T vs C: OR =1.37, 95% CI =1.18, 1.59), while the results for polymorphisms of rs7958904, rs4759314, rs874945, and rs1899663 were insignificant.
|
29497311 |
2018 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
No significant association was noted between the HOTAIR rs4759314 polymorphism and cancer risk in a Chinese population.
|
27685928 |
2017 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
However, no significant association was identified between the rs874945, rs4759314 and rs1899663 polymorphisms and cancer susceptibility.
|
27791260 |
2017 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
rs920778, rs7958904 and rs874945 but not rs4759314 and rs1899663 loci were significantly related to cancer risk, among of which rs920778 and rs874945 increased and rs7958904 decreased cancer risk, respectively.
|
27965458 |
2017 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
Overall, no significant associations between the HOTAIR polymorphisms (rs920778, rs4759314 and rs1899663) and cancer r</span>isk were observed.
|
27010768 |
2016 |
|
rs4759314
|
|
Primary malignant neoplasm
|
|
0.080 |
GeneticVariation
|
BEFREE |
In conclusion, the results indicated that HOTAIR polymorphism rs920778 was more generally associated with cancer risk, particularly in Asians, while rs4759314 was a risk factor for gastric cancer.
|
27246974 |
2016 |