rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Further subgroup analyses showed that rs1333040, rs1333049 and rs2383207 polymorphisms were significantly correlated with the risk of CAD in East Asians, rs2383206 and rs10757274 polymorphisms were significantly correlated with the risk of CAD in West Asians, while rs2383206, rs10757274 and rs10757278 polymorphisms were significantly correlated with the risk of CAD in Caucasians.
|
30814313 |
2019 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Pooled overall analyses showed that rs1333040 (dominant model: P < 0.0001; recessive model: P < 0.0001; allele model: P < 0.0001), rs1333049 (dominant model: P = 0.02; allele model: P = 0.02) and rs2383207 (additive model: P = 0.004; allele model: P = 0.03) polymorphisms were significantly associated with the likelihood of CAD.
|
30387168 |
2019 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The polymorphic variants of Apo-A5; rs2266788 (C), 9p21.3; rs1333049 (C) rs2383207 (A) are associated with CAD, its severity and exerts the risk of MI in North Indian population.
|
29309886 |
2018 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
In conclusion, this meta-analysis suggested that ANRIL rs2383207 polymorphism is associated with CAD risk.
|
27894414 |
2016 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The risk allele G of rs2383207 was associated with severity of CAD estimated by the Gensini score (P = 3.6×10(-5) ).
|
27461153 |
2016 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
The rs2383207 and rs1333049 SNPs on 9p21 chromosome were significantly associated with the risk and severity of CAD in the Turkish population.
|
25333979 |
2015 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
We identified two 9p21.3-variants, rs4977574 (P < 4×10(-4)) and rs2383207 (P < 1.5×10(-3)) that were associated with severity of CAD in subjects without T2D.
|
23343465 |
2013 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Further, we evaluated nine additional SNPs, of which two SNPs flanking rs2383207 (rs1537375 [p = 2.4 × 10(-5)] and rs1537374 [p = 5.6 × 10(-5)]) were also strongly associated with CAD.
|
20858033 |
2011 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Conclusions The rs10757278 and rs2383207 variants are determinants for early-onset coronary artery disease.
|
18459066 |
2009 |
rs2383207
|
|
Coronary Artery Disease
|
|
0.100 |
GeneticVariation
|
BEFREE |
Genome-wide single nucleotide polymorphism (SNP) association studies recently identified four SNPs (rs10757274, rs2383206, rs2383207, and rs10757278) on chromosome 9p21 that were associated with coronary artery disease (CAD) and myocardial infarction (MI) in Caucasian populations from northern Europe and North America.
|
18066490 |
2008 |