Source: BEFREE

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4299376
rs4299376
ABCG8 ; LOC102725159
CUI: C1956346
Disease: Coronary Artery Disease
Coronary Artery Disease 		0.710 GeneticVariation BEFREE Based on the findings that rs4299376</span> was associated with a 2.75 mg/dL decrease in LDL-C and a 5% decrease in risk of CAD outcomes, we estimated that cholestyramine was associated with an odds ratio for CA</span>D of 0.63 (95% CI 0.52-0.77; P=6.3×10(-6)) and colesevelam with an odds ratio of 0.64 (95% CI 0.52-0.79, P=4.3×10(-5)), which were not statistically different from BAS clinical trials (P>0.05). 26043746

2015