DisGeNET - a database of gene-disease associations

Source: CLINVAR

Disease: Leukemia, Myelocytic, Acute ×

Variant: rs587782329 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs587782329

TP53

CUI:	C0023467
Disease:	Leukemia, Myelocytic, Acute

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

CLINVAR

Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice.

24381225

2014

dbSNP:

rs587782329

TP53

CUI:	C0023467
Disease:	Leukemia, Myelocytic, Acute

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

CLINVAR

Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.

24641375

2014

dbSNP:

rs587782329

TP53

CUI:	C0023467
Disease:	Leukemia, Myelocytic, Acute

Leukemia, Myelocytic, Acute

0.700

GeneticVariation

CLINVAR

Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients.

24487413

2014