Source: CLINVAR

Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1057519730
rs1057519730
MAP2K1
CUI: C0025202
Disease: melanoma
melanoma 		G 0.700 CausalMutation CLINVAR Preexisting MEK1 exon 3 mutations in V600E/KBRAF melanomas do not confer resistance to BRAF inhibitors. 22588879

2012
dbSNP: rs1057519730
rs1057519730
MAP2K1
CUI: C0025202
Disease: melanoma
melanoma 		G 0.700 CausalMutation CLINVAR Exome sequencing identifies recurrent somatic MAP2K1 and MAP2K2 mutations in melanoma. 22197931

2011